GL1X · GenesisL1 explorer

Ligand · GQT

GQT · (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl) phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide

GQT, (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl) phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide (C30 H43 N7 O6 S, 629.8 g/mol)…

Component
GQT
Formula
C30 H43 N7 O6 S
Class
ligand
Structures
4
PDB entries
3

Binding sites

GQT in 4 structures; the first of them:

  • 6HTR · Yeast 20S proteasome with human beta2c (S171G) in complex with 13 · GQT H301 · binds THR1, ALA20, THR21, GLU22, CYS31, SER32, LYS33, HIS35 and 10 more
  • 6HTR · Yeast 20S proteasome with human BETA2C (S171G) in complex with 13 · GQT H301 · binds THR1, ALA20, THR21, GLU22, CYS31, SER32, LYS33, HIS35 and 10 more
  • 6HVA · Yeast 20S proteasome with human BETA2I (1-53) in complex with 13 · GQT H301 · binds THR1, ALA20, THR21, ASN22, ALA27, CYS31, GLU32, LYS33 and 10 more
  • 6HW3 · Yeast 20S proteasome in complex with 13 · GQT H301 · binds THR1, SER20, THR21, GLN22, ALA27, CYS31, ALA32, LYS33 and 11 more

Residues it binds most

ALA 16, GLY 16, THR 16, SER 16, ASP 16, LYS 16, CYS 8, GLU 8, VAL 10, HIS 8 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.