UniProt P40019
Histone H2A.Z-specific chaperone CHZ1 (P40019)
Histone H2A.Z-specific chaperone CHZ1 (UniProt P40019): 5 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40019
- Protein
- Histone H2A.Z-specific chaperone CHZ1
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
6 records of P40019 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JSS | NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B | solution nmr | B | — | — |
| 2JSS | NMR structure of chaperone CHZ1 complexed with histone H2A.Z-H2B | solution nmr | B | — | — |
| 6AE8 | Structure insight into histone chaperone Chz1-mediated H2A.Z recognition and replacement | x-ray diffraction | C, D | — | 1 (best 0.52) |
| 6AE8 | Structure insight into histone chaperone CHZ1-mediated H2A.Z recognition and replacement | x-ray diffraction | C, D | — | — |
| 8QZ0 | SWR1-hexasome-dimer complex | electron microscopy | K | — | — |
| P40019 | AlphaFold monomer V2.0 prediction for histone H2A.Z-specific chaperone CHZ1 (P40019) | predicted | A | — | — |
Experiment against prediction
- 6AE8 chain D against the predicted model P40019: TM-score 0.38, RMSD 1.77 Å
- 6AE8 chain D against the predicted model P40019: TM-score 0.38, RMSD 1.77 Å
- 6AE8 chain C against the predicted model P40019: TM-score 0.36, RMSD 1.49 Å
- 6AE8 chain C against the predicted model P40019: TM-score 0.36, RMSD 1.49 Å
- 8QZ0 chain K against the predicted model P40019: TM-score 0.30, RMSD 2.87 Å
- 2JSS chain B against the predicted model P40019: TM-score 0.28, RMSD 4.17 Å
- 2JSS chain B against the predicted model P40019: TM-score 0.28, RMSD 4.17 Å
Elsewhere
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