UniProt P39897
HTH-type transcriptional regulator MtrR (P39897)
HTH-type transcriptional regulator MtrR (UniProt P39897): 8 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P39897
- Protein
- HTH-type transcriptional regulator MtrR
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 31 · 5 records with a druggable one
Structures
9 records of P39897 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6OF0 | Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump… | x-ray diffraction | A, B, C, D | PO4 | 8 (best 0.79) |
| 6OF0 | Structural basis for multidrug recognition and antimicrobial resistance by mtrr, an efflux pump… | x-ray diffraction | A, B, C, D | PO4 | — |
| 7JNP | MtrR bound to the rpoH operator from Neisseria gonorrhoeae | x-ray diffraction | A, B | CA | — |
| 7JNP | Mtrr bound to the rpoh operator from neisseria gonorrhoeae | x-ray diffraction | A, B | CA | — |
| 7JU3 | Mtrr bound to the mtrcde operator from neisseria gonorrhoeae | x-ray diffraction | A, B | CA | — |
| 8FW0 | MtrR from Neisseria gonorrhoeae bound to beta-Estradiol | x-ray diffraction | A, B, C, D | EST, PO4 | 9 (best 0.82) |
| 8FW3 | MtrR from Neisseria gonorrhoeae bound to Testosterone | x-ray diffraction | C, D, A, B | TES, PO4 | 8 (best 0.79) |
| 8SSH | MtrR from Neisseria gonorrhoeae bound to Ethinyl Estradiol | x-ray diffraction | C, D, A, B | 3WF, PO4 | 5 (best 0.81) |
| P39897 | AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator mtrr (P39897) | predicted | A | — | 1 (best 0.77) |
Ligands
Experiment against prediction
- 6OF0 chain D against the predicted model P39897: TM-score 0.99, RMSD 0.54 Å
- 6OF0 chain D against the predicted model P39897: TM-score 0.99, RMSD 0.54 Å
- 6OF0 chain A against the predicted model P39897: TM-score 0.99, RMSD 0.58 Å
- 6OF0 chain A against the predicted model P39897: TM-score 0.99, RMSD 0.58 Å
- 8FW3 chain B against the predicted model P39897: TM-score 0.99, RMSD 0.59 Å
- 8FW0 chain A against the predicted model P39897: TM-score 0.99, RMSD 0.61 Å
- 8FW3 chain D against the predicted model P39897: TM-score 0.99, RMSD 0.62 Å
- 8FW0 chain C against the predicted model P39897: TM-score 0.99, RMSD 0.62 Å
- 8FW3 chain C against the predicted model P39897: TM-score 0.99, RMSD 0.62 Å
- 8FW0 chain B against the predicted model P39897: TM-score 0.99, RMSD 0.63 Å
Elsewhere
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