UniProt P38861
60S ribosomal export protein NMD3 (P38861)
60S ribosomal export protein NMD3 (UniProt P38861): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38861
- Protein
- 60S ribosomal export protein NMD3
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 3 records with a druggable one
Structures
12 records of P38861 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5H4P | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | electron microscopy | w | — | — |
| 5T62 | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | V | — | 1 (best 0.85) |
| 5T6R | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | V | — | — |
| 6N8K | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | electron microscopy | v | — | — |
| 6N8L | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | electron microscopy | v | — | — |
| 6N8M | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | electron microscopy | V | — | — |
| 6N8N | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | electron microscopy | V | — | — |
| 6N8O | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | electron microscopy | V | — | — |
| 6QIK | Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles | electron microscopy | w | ZN | — |
| 6RI5 | Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles | electron microscopy | w | ZN | — |
| 6S05 | Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles | electron microscopy | w | ZN | 2 (best 0.86) |
| P38861 | AlphaFold monomer V2.0 prediction for 60S ribosomal export protein NMD3 (P38861) | predicted | A | — | 6 (best 0.73) |
Ligands
- ZN · Zinc ion · in 3 records
Experiment against prediction
- 5T6R chain V against the predicted model P38861: TM-score 0.97, RMSD 1.13 Å
- 5H4P chain w against the predicted model P38861: TM-score 0.97, RMSD 0.97 Å
- 6N8K chain v against the predicted model P38861: TM-score 0.97, RMSD 1.16 Å
- 5T62 chain V against the predicted model P38861: TM-score 0.96, RMSD 1.53 Å
- 6N8M chain V against the predicted model P38861: TM-score 0.94, RMSD 1.87 Å
- 6N8L chain v against the predicted model P38861: TM-score 0.94, RMSD 1.98 Å
- 6QIK chain w against the predicted model P38861: TM-score 0.81, RMSD 4.02 Å
- 6S05 chain w against the predicted model P38861: TM-score 0.81, RMSD 4.00 Å
- 6N8N chain V against the predicted model P38861: TM-score 0.79, RMSD 4.08 Å
- 6N8O chain V against the predicted model P38861: TM-score 0.78, RMSD 4.01 Å
Elsewhere
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