UniProt P38779
Proteasome-interacting protein CIC1 (P38779)
Proteasome-interacting protein CIC1 (UniProt P38779): 33 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38779
- Protein
- Proteasome-interacting protein CIC1
- Experimental structures
- 33
- Predicted models
- 1
- Pockets
- 29 · 17 records with a druggable one
Structures
34 records of P38779 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | K | — | — |
| 5Z3G | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | electron microscopy | H | — | 3 (best 0.86) |
| 5Z3G | Cryo-EM structure of a nucleolar pre-60S ribosome (RPF1-tap) | electron microscopy | H | — | — |
| 6C0F | Yeast nucleolar pre-60S ribosomal subunit (state 2) | electron microscopy | K | — | — |
| 6C0F | Yeast nucleolar pre-60S ribosomal subunit (state 2) | electron microscopy | K | — | — |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | K | — | 1 (best 0.86) |
| 6EM1 | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | K | — | 1 (best 0.87) |
| 6EM3 | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | 1 (best 0.65) |
| 6EM3 | State a architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | — |
| 6EM4 | State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | 1 (best 0.72) |
| 6EM4 | State B architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | — |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | — |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | K | — | — |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | K | — | — |
| 6YLX | pre-60S State NE1 (TAP-Flag-Nop53) | electron microscopy | K | — | 1 (best 0.87) |
| 6YLY | pre-60S State NE2 (TAP-Flag-Nop53) | electron microscopy | K | — | 1 (best 0.89) |
| 7BTB | Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22… | electron microscopy | K | — | — |
| 7NAC | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | electron microscopy | K | — | — |
| 7OHP | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut… | electron microscopy | K | — | 2 (best 0.81) |
| 7OHQ | Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae | electron microscopy | K | — | — |
| 7OHR | Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae | electron microscopy | K | — | 1 (best 0.86) |
| 7OHS | Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae | electron microscopy | K | — | 2 (best 0.82) |
| 7OHV | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut… | electron microscopy | K | — | 1 (best 0.85) |
| 7OHX | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut… | electron microscopy | K | — | 2 (best 0.81) |
| 7R6Q | State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | electron microscopy | K | — | 5 (best 0.86) |
| 7R7A | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | electron microscopy | K | — | 2 (best 0.86) |
| 7U0H | State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | electron microscopy | K | — | — |
| 7UOO | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | electron microscopy | K | — | — |
| 7UQB | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A… | electron microscopy | K | — | — |
| 7UQZ | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain | electron microscopy | K | — | — |
| 8E5T | Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate | electron microscopy | K | — | 2 (best 0.77) |
| 8V83 | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | electron microscopy | K | — | 1 (best 0.85) |
| 8V84 | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | electron microscopy | K | — | 2 (best 0.84) |
| P38779 | AlphaFold monomer V2.0 prediction for proteasome-interacting protein CIC1 (P38779) | predicted | A | — | — |
Experiment against prediction
- 6EM4 chain K against the predicted model P38779: TM-score 0.97, RMSD 0.97 Å
- 6EM4 chain K against the predicted model P38779: TM-score 0.97, RMSD 0.97 Å
- 6EM3 chain K against the predicted model P38779: TM-score 0.97, RMSD 0.97 Å
- 6EM3 chain K against the predicted model P38779: TM-score 0.97, RMSD 0.97 Å
- 8E5T chain K against the predicted model P38779: TM-score 0.97, RMSD 1.18 Å
- 7OHQ chain K against the predicted model P38779: TM-score 0.97, RMSD 1.17 Å
- 7OHX chain K against the predicted model P38779: TM-score 0.96, RMSD 1.18 Å
- 3JCT chain K against the predicted model P38779: TM-score 0.96, RMSD 1.43 Å
- 6EM5 chain K against the predicted model P38779: TM-score 0.96, RMSD 1.24 Å
- 6EM5 chain K against the predicted model P38779: TM-score 0.96, RMSD 1.24 Å
Elsewhere
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