UniProt P37727
Rab proteins geranylgeranyltransferase component a 1 (P37727)
Rab proteins geranylgeranyltransferase component a 1 (UniProt P37727): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P37727
- Protein
- Rab proteins geranylgeranyltransferase component a 1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P37727 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LTX | Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid | x-ray diffraction | R | — | — |
| 1LTX | Structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid | x-ray diffraction | R | — | — |
| 1VG0 | The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein | x-ray diffraction | A | — | — |
| 1VG0 | The crystal structures of the rep-1 protein in complex with monoprenylated RAB7 protein | x-ray diffraction | A | — | — |
| 1VG9 | The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein | x-ray diffraction | A, C, E, G | — | — |
| 1VG9 | The crystal structures of the rep-1 protein in complex with C- terminally truncated RAB7 protein | x-ray diffraction | A, C, E, G | — | — |
| P37727 | AlphaFold monomer V2.0 prediction for rab proteins geranylgeranyltransferase component a 1 (P37727) | predicted | A | — | 7 (best 0.68) |
Experiment against prediction
- 1VG0 chain A against the predicted model P37727: TM-score 1.00, RMSD 0.53 Å
- 1VG0 chain A against the predicted model P37727: TM-score 1.00, RMSD 0.53 Å
- 1VG9 chain C against the predicted model P37727: TM-score 0.99, RMSD 0.72 Å
- 1VG9 chain C against the predicted model P37727: TM-score 0.99, RMSD 0.72 Å
- 1VG9 chain E against the predicted model P37727: TM-score 0.98, RMSD 1.40 Å
- 1VG9 chain E against the predicted model P37727: TM-score 0.98, RMSD 1.40 Å
- 1VG9 chain A against the predicted model P37727: TM-score 0.98, RMSD 1.42 Å
- 1VG9 chain A against the predicted model P37727: TM-score 0.98, RMSD 1.42 Å
- 1LTX chain R against the predicted model P37727: TM-score 0.97, RMSD 1.36 Å
- 1LTX chain R against the predicted model P37727: TM-score 0.97, RMSD 1.36 Å
Elsewhere
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