UniProt P36629
Splicing factor U2AF 59 kDa subunit (P36629)
Splicing factor U2AF 59 kDa subunit (UniProt P36629): 7 experimental structures and 1 predicted model on GenesisL1, 46 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P36629
- Protein
- Splicing factor U2AF 59 kDa subunit
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 46 · 2 records with a druggable one
Structures
8 records of P36629 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YH8 | Structure of yeast U2AF complex | x-ray diffraction | B | — | — |
| 4YH8 | Structure of yeast U2AF complex | x-ray diffraction | B | — | — |
| 7C06 | Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-uaggu. | x-ray diffraction | B, E, H, K, N, Q, T, W, Z | — | — |
| 7C07 | Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA. | x-ray diffraction | B, E, H, K, N, Q, T, W, Z | — | 20 (best 0.87) |
| 7C07 | Crystal structure of yeast U2AF1 complex bound to 5'-aaggu RNA. | x-ray diffraction | B, E, H, K, N, Q, T, W, Z | — | — |
| 7C08 | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | x-ray diffraction | B, E, H, K, N, Q, T, W, Z | — | 20 (best 0.87) |
| 7C08 | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-uaggu. | x-ray diffraction | B, E, H, K, N, Q, T, W, Z | — | — |
| P36629 | AlphaFold monomer V2.0 prediction for splicing factor U2AF 59 kda subunit (P36629) | predicted | A | — | 6 (best 0.36) |
Experiment against prediction
- 7C08 chain K against the predicted model P36629: TM-score 0.57, RMSD 3.01 Å
- 7C08 chain K against the predicted model P36629: TM-score 0.57, RMSD 3.01 Å
- 7C07 chain T against the predicted model P36629: TM-score 0.56, RMSD 2.24 Å
- 7C07 chain T against the predicted model P36629: TM-score 0.56, RMSD 2.24 Å
- 7C07 chain Q against the predicted model P36629: TM-score 0.56, RMSD 2.68 Å
- 7C08 chain E against the predicted model P36629: TM-score 0.56, RMSD 2.65 Å
- 7C08 chain E against the predicted model P36629: TM-score 0.56, RMSD 2.65 Å
- 7C07 chain H against the predicted model P36629: TM-score 0.56, RMSD 2.77 Å
- 7C07 chain H against the predicted model P36629: TM-score 0.56, RMSD 2.77 Å
- 7C06 chain Z against the predicted model P36629: TM-score 0.56, RMSD 2.77 Å
Elsewhere
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