UniProt P36186
Triosephosphate isomerase (P36186)
Triosephosphate isomerase (UniProt P36186), EC 5.3.1.1: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 58 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P36186
- Protein
- Triosephosphate isomerase
- EC
- 5.3.1.1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 58 · 2 records with a druggable one
Structures
11 records of P36186 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DP3 | Crystal structure of a double mutant (C202A/A198V) of Triosephosphate isomerase from giardia lamblia | x-ray diffraction | A | SO4 | 2 (best 0.40) |
| 2DP3 | Crystal structure of a double mutant (C202A/A198V) of triosephosphate isomerase from giardia lamblia | x-ray diffraction | A | SO4 | 2 (best 0.40) |
| 3PF3 | Crystal structure of a mutant (C202A) of Triosephosphate isomerase from Giardia lamblia derivatized… | x-ray diffraction | A | SO4, CA | 2 (best 0.46) |
| 3PF3 | Crystal structure of a mutant (C202A) of triosephosphate isomerase from giardia lamblia derivatized… | x-ray diffraction | A | SO4, CA | 2 (best 0.46) |
| 4BI5 | Crystal structure of a double mutant (C202A and C222D) of triosephosphate isomerase from giardia… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | 20 (best 0.82) |
| 4BI5 | Crystal structure of a double mutant (C202A and C222D) of triosephosphate isomerase from giardia… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | 20 (best 0.82) |
| 4BI6 | Crystal structure of a triple mutant (A198V, C202A and C222N) of triosephosphate isomerase from… | x-ray diffraction | A | PGA | 2 (best 0.44) |
| 4BI6 | Crystal structure of a triple mutant (A198V, C202A and C222N) of triosephosphate isomerase from… | x-ray diffraction | A | PGA | 2 (best 0.44) |
| 4BI7 | Crystal structure of a mutant (C202A) of triosephosphate isomerase from giardia lamblia complexed… | x-ray diffraction | A | PGA, SO4 | 2 (best 0.42) |
| 4BI7 | Crystal structure of a mutant (C202A) of triosephosphate isomerase from giardia lamblia. complexed… | x-ray diffraction | A | PGA, SO4 | 2 (best 0.42) |
| P36186 | AlphaFold monomer V2.0 prediction for triosephosphate isomerase (P36186) | predicted | A | — | 2 (best 0.41) |
Ligands
Experiment against prediction
- 2DP3 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.33 Å
- 2DP3 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.33 Å
- 4BI7 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.39 Å
- 4BI7 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.39 Å
- 3PF3 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.39 Å
- 3PF3 chain A against the predicted model P36186: TM-score 1.00, RMSD 0.39 Å
- 4BI6 chain A against the predicted model P36186: TM-score 0.99, RMSD 0.49 Å
- 4BI6 chain A against the predicted model P36186: TM-score 0.99, RMSD 0.49 Å
- 4BI5 chain A against the predicted model P36186: TM-score 0.98, RMSD 0.98 Å
- 4BI5 chain A against the predicted model P36186: TM-score 0.98, RMSD 0.98 Å
Elsewhere
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