UniProt P36012
Histone H3-like centromeric protein CSE4 (P36012)
Histone H3-like centromeric protein CSE4 (UniProt P36012): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P36012
- Protein
- Histone H3-like centromeric protein CSE4
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 43 · 8 records with a druggable one
Structures
10 records of P36012 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2L5A | Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3 | solution nmr | A | — | 4 (best 0.72) |
| 2L5A | Structural basis for recognition of centromere specific histone H3 variant by nonhistone SCM3 | solution nmr | A | — | 4 (best 0.72) |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | a, e | — | 4 (best 0.78) |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | a, e | — | 4 (best 0.78) |
| 6UPH | Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution | electron microscopy | A, E | — | 11 (best 0.73) |
| 6UPH | Structure of a yeast centromeric nucleosome at 2.7 ångström resolution | electron microscopy | A, E | — | 11 (best 0.73) |
| 8OW0 | Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | electron microscopy | e, a | — | 3 (best 0.77) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | e, a | — | 2 (best 0.80) |
| 8T0P | Structure of Cse4 bound to Ame1 and Okp1 | x-ray diffraction | C | SO4 | — |
| P36012 | AlphaFold monomer V2.0 prediction for histone H3-like centromeric protein CSE4 (P36012) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 6UPH chain A against the predicted model P36012: TM-score 0.95, RMSD 0.91 Å
- 6UPH chain A against the predicted model P36012: TM-score 0.95, RMSD 0.91 Å
- 6UPH chain E against the predicted model P36012: TM-score 0.93, RMSD 1.07 Å
- 6UPH chain E against the predicted model P36012: TM-score 0.93, RMSD 1.07 Å
- 8OW1 chain e against the predicted model P36012: TM-score 0.92, RMSD 1.22 Å
- 8OW1 chain a against the predicted model P36012: TM-score 0.92, RMSD 1.22 Å
- 8OW0 chain a against the predicted model P36012: TM-score 0.91, RMSD 1.21 Å
- 8OW0 chain e against the predicted model P36012: TM-score 0.91, RMSD 1.21 Å
- 6QLD chain a against the predicted model P36012: TM-score 0.90, RMSD 1.21 Å
- 6QLD chain a against the predicted model P36012: TM-score 0.90, RMSD 1.21 Å
Elsewhere
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