UniProt P35221
Catenin alpha-1 (P35221)
Catenin alpha-1 (UniProt P35221): 13 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35221
- Protein
- Catenin alpha-1
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
14 records of P35221 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H6G | alpha-catenin M-domain | x-ray diffraction | A, B | — | — |
| 1H6G | Alpha-catenin M-domain | x-ray diffraction | A, B | — | — |
| 1L7C | alpha-catenin fragment, residues 385-651 | x-ray diffraction | A, B, C | — | — |
| 1L7C | Alpha-catenin fragment, residues 385-651 | x-ray diffraction | A, B, C | — | — |
| 4EHP | Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin… | x-ray diffraction | B | — | — |
| 4EHP | Crystal structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin… | x-ray diffraction | B | — | — |
| 4IGG | Full-length human alpha-catenin crystal structure | x-ray diffraction | A, B | — | — |
| 4IGG | Full-length human alpha-catenin crystal structure | x-ray diffraction | A, B | — | — |
| 6UPV | Alpha-E-catenin ABD-F-actin complex | electron microscopy | M, L | — | 7 (best 0.75) |
| 6UPV | Alpha-E-catenin abd-F-actin complex | electron microscopy | M, L | — | — |
| 7UTJ | Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin | electron microscopy | G, H, I, K, L, Z | — | — |
| 9BL3 | KIR3DL1*114 in complex with HLA-B*57:03 presenting the AW10 peptide | x-ray diffraction | C | — | — |
| 9BL4 | KIR3DL1*086 in complex with HLA-B*57:03 presenting the AW10 peptide | x-ray diffraction | C | — | 2 (best 0.74) |
| P35221 | AlphaFold monomer V2.0 prediction for catenin alpha-1 (P35221) | predicted | A | — | — |
Experiment against prediction
- 7UTJ chain H against the predicted model P35221: TM-score 0.76, RMSD 3.14 Å
- 7UTJ chain Z against the predicted model P35221: TM-score 0.76, RMSD 3.15 Å
- 7UTJ chain I against the predicted model P35221: TM-score 0.76, RMSD 3.15 Å
- 7UTJ chain K against the predicted model P35221: TM-score 0.76, RMSD 3.15 Å
- 7UTJ chain L against the predicted model P35221: TM-score 0.76, RMSD 3.11 Å
- 7UTJ chain G against the predicted model P35221: TM-score 0.76, RMSD 3.15 Å
- 6UPV chain M against the predicted model P35221: TM-score 0.74, RMSD 3.28 Å
- 6UPV chain M against the predicted model P35221: TM-score 0.74, RMSD 3.28 Å
- 6UPV chain L against the predicted model P35221: TM-score 0.74, RMSD 3.35 Å
- 6UPV chain L against the predicted model P35221: TM-score 0.74, RMSD 3.35 Å
Elsewhere
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