UniProt P33681
T-lymphocyte activation antigen CD80 (P33681)
T-lymphocyte activation antigen CD80 (UniProt P33681): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33681
- Protein
- T-lymphocyte activation antigen CD80
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 0 records with a druggable one
Structures
7 records of P33681 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DR9 | Crystal structure of a soluble form of B7-1 (CD80) | x-ray diffraction | A | — | — |
| 1DR9 | Crystal structure of a soluble form of B7-1 (CD80) | x-ray diffraction | A | — | — |
| 1I8L | Human B7-1/CTLA-4 co-stimulatory complex | x-ray diffraction | A, B | — | — |
| 1I8L | Human B7-1/CTLA-4 co-stimulatory complex | x-ray diffraction | A, B | — | — |
| 7TPS | Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1 | x-ray diffraction | A, C | NAG | 5 (best 0.38) |
| 7TPS | Crystal structure of alpn-202 (engineered CD80 vigd) in complex with pd-L1 | x-ray diffraction | A, C | NAG | — |
| P33681 | AlphaFold monomer V2.0 prediction for T-lymphocyte activation antigen CD80 (P33681) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 7TPS chain A against the predicted model P33681: TM-score 0.96, RMSD 0.74 Å
- 7TPS chain A against the predicted model P33681: TM-score 0.96, RMSD 0.74 Å
- 7TPS chain C against the predicted model P33681: TM-score 0.96, RMSD 0.78 Å
- 7TPS chain C against the predicted model P33681: TM-score 0.96, RMSD 0.78 Å
- 1I8L chain A against the predicted model P33681: TM-score 0.75, RMSD 3.29 Å
- 1I8L chain A against the predicted model P33681: TM-score 0.75, RMSD 3.29 Å
- 1I8L chain B against the predicted model P33681: TM-score 0.75, RMSD 3.38 Å
- 1I8L chain B against the predicted model P33681: TM-score 0.75, RMSD 3.38 Å
- 1DR9 chain A against the predicted model P33681: TM-score 0.75, RMSD 3.31 Å
- 1DR9 chain A against the predicted model P33681: TM-score 0.75, RMSD 3.31 Å
Elsewhere
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