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UniProt P33527

Multidrug resistance-associated protein 1 (P33527)

Multidrug resistance-associated protein 1 (UniProt P33527), EC 7.6.2.2, 7.6.2.3: 8 experimental structures on GenesisL1, 2 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P33527
Protein
Multidrug resistance-associated protein 1
EC
7.6.2.2, 7.6.2.3
Experimental structures
8
Predicted models
0
Ligands
2
Pockets
60 · 3 records with a druggable one

Structures

8 records of P33527 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2CBZStructure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1x-ray diffractionA——
2CBZStructure of the human multidrug resistance protein 1 nucleotide binding domain 1x-ray diffractionA——
4C3ZNucleotide-free crystal structure of nucleotide-binding domain 1 from human MRP1 supports a…x-ray diffractionA——
4C3ZNucleotide-free crystal structure of nucleotide-binding domain 1 from human MRP1 supports a…x-ray diffractionA——
8VT4Cryo-EM structure of human ABC transporter ABCC1electron microscopyA, BY0120 (best 0.86)
8VUXCryo-EM structure of human ABC transporter (hABCC1) bound to cGAMPelectron microscopyA, BY01, 1SY20 (best 0.87)
8VVCCryo-EM structure of human ABC transporter (hABCC1) with nucleotide-binding domain 2electron microscopyA—20 (best 0.87)
P33527AlphaFold monomer V2.0 prediction for multidrug resistance-associated protein 1 (P33527)———

Ligands

  • Y01 · Cholesterol hemisuccinate · in 2 records
  • 1SY · cGAMP · in 1 record

Elsewhere

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