UniProt P33302
Pleiotropic ABC efflux transporter of multiple drugs (P33302)
Pleiotropic ABC efflux transporter of multiple drugs (UniProt P33302): 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 49 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P33302
- Protein
- Pleiotropic ABC efflux transporter of multiple drugs
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 49 · 3 records with a druggable one
Structures
7 records of P33302 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7P03 | Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation without… | electron microscopy | A | — | 12 (best 0.82) |
| 7P03 | Cryo-EM structure of PDR5 from saccharomyces cerevisiae in inward- facing conformation without… | electron microscopy | A | — | — |
| 7P04 | Cryo-EM structure of PDR5 from saccharomyces cerevisiae in inward- facing conformation with ADP/ATP | electron microscopy | A | ATP, ADP | — |
| 7P05 | Cryo-EM structure of PDR5 from saccharomyces cerevisiae in inward- facing conformation with ADP/ATP… | electron microscopy | A | ATP, ADP, RHQ | — |
| 7P06 | Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in outward-facing conformation with… | electron microscopy | A | ATP, MG, AOV | 17 (best 0.86) |
| 7P06 | Cryo-EM structure of PDR5 from saccharomyces cerevisiae in outward- facing conformation with… | electron microscopy | A | ATP, MG, AOV | — |
| P33302 | AlphaFold monomer V2.0 prediction for pleiotropic ABC efflux transporter of multiple drugs (P33302) | predicted | A | — | 20 (best 0.84) |
Ligands
Experiment against prediction
- 7P06 chain A against the predicted model P33302: TM-score 0.97, RMSD 2.14 Å
- 7P06 chain A against the predicted model P33302: TM-score 0.97, RMSD 2.14 Å
- 7P04 chain A against the predicted model P33302: TM-score 0.93, RMSD 3.12 Å
- 7P05 chain A against the predicted model P33302: TM-score 0.93, RMSD 3.13 Å
- 7P03 chain A against the predicted model P33302: TM-score 0.92, RMSD 3.22 Å
- 7P03 chain A against the predicted model P33302: TM-score 0.92, RMSD 3.22 Å
Elsewhere
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