UniProt P32585
Mediator of RNA polymerase II transcription subunit 18 (P32585)
Mediator of RNA polymerase II transcription subunit 18 (UniProt P32585): 21 experimental structures on GenesisL1, 12 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P32585
- Protein
- Mediator of RNA polymerase II transcription subunit 18
- Experimental structures
- 21
- Predicted models
- 0
- Pockets
- 12 · 4 records with a druggable one
Structures
21 records of P32585 in the MolNFT archive: 21 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HZM | Structure of the Mediator head subcomplex Med18/20 | x-ray diffraction | B, D, F, H | — | — |
| 2HZM | Structure of the mediator head subcomplex MED18/20 | x-ray diffraction | B, D, F, H | — | — |
| 2HZS | Structure of the Mediator head submodule Med8C/18/20 | x-ray diffraction | B, D, F, H | — | — |
| 2HZS | Structure of the mediator head submodule MED8C/18/20 | x-ray diffraction | B, D, F, H | — | — |
| 3J1O | Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module | electron microscopy | L | — | — |
| 3J1O | Cryo-EM MAP of a yeast minimal preinitiation complex interacting with the mediator head module | electron microscopy | L | — | — |
| 3RJ1 | Architecture of the Mediator Head module | x-ray diffraction | E, L, S | — | — |
| 3RJ1 | Architecture of the mediator head module | x-ray diffraction | E, L, S | — | — |
| 4GWP | Structure of the Mediator Head Module from S. cerevisiae | x-ray diffraction | E | — | — |
| 4GWP | Structure of the mediator head module from S. cerevisiae | x-ray diffraction | E | — | — |
| 4GWQ | Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal… | x-ray diffraction | E | — | — |
| 4GWQ | Structure of the mediator head module from S. cerevisiae in complex with the carboxy-terminal… | x-ray diffraction | E | — | — |
| 4V1O | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | electron microscopy | X | — | — |
| 4V1O | Architecture of the RNA polymerase II-mediator core transcription initiation complex | electron microscopy | X | — | — |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | e | — | 2 (best 0.84) |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | e | — | — |
| 5SVA | Mediator-RNA polymerase II pre-initiation complex | electron microscopy | Q | — | — |
| 7UIF | Mediator-PIC Early (Core B) | electron microscopy | r | — | 3 (best 0.83) |
| 7UIG | Mediator-PIC Early (Mediator A) | electron microscopy | r | — | 2 (best 0.82) |
| 7UIO | Mediator-PIC Early (Composite Model) | electron microscopy | Ar, Br | — | 5 (best 0.87) |
| P32585 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 18… | — | — | — |
Elsewhere
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