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UniProt P32418

Sodium/calcium exchanger 1 (P32418)

Sodium/calcium exchanger 1 (UniProt P32418): 4 experimental structures on GenesisL1, 3 ligands bound, 29 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P32418
Protein
Sodium/calcium exchanger 1
Experimental structures
4
Predicted models
0
Ligands
3
Pockets
29 · 3 records with a druggable one

Structures

4 records of P32418 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8JP0structure of human sodium-calciumexchanger NCX1electron microscopyAEKY8 (best 0.79)
8SGICryo-EM structure of human NCX1 in complex with SEA0400electron microscopyAEKY, CA, NA11 (best 0.82)
8SGTCryo-EM structure of human NCX1 in Ca2+ bound, activated state (group II in the presence of 0.5 mM…electron microscopyACA10 (best 0.73)
P32418AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 1 (P32418)———

Ligands

  • CA · Calcium ion · in 2 records
  • EKY · 2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline · in 2 records
  • NA · Sodium ion · in 1 record

Elsewhere

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