UniProt P32119
Peroxiredoxin-2 (P32119)
Peroxiredoxin-2 (UniProt P32119), EC 1.11.1.15, 1.11.1.24: 12 experimental structures on GenesisL1, 1 ligand bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P32119
- Protein
- Peroxiredoxin-2
- EC
- 1.11.1.15, 1.11.1.24
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 60 · 3 records with a druggable one
Structures
12 records of P32119 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QMV | thioredoxin peroxidase B from red blood cells | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1QMV | Thioredoxin peroxidase B from red blood cells | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 5B8A | Crystal structure of oxidized chimeric ECAHPC1-186-yfskhn | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 5B8B | Crystal structure of reduced chimeric E.COLI AHPC1-186-yfskhn | x-ray diffraction | A, B, I, J, C, D, F, E, G, H | — | — |
| 5IJT | Human Peroxiredoxin 2 Oxidized (SS) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | ZN | 20 (best 0.75) |
| 5IJT | Human peroxiredoxin 2 oxidized (ss) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 7KIZ | reduced human peroxiredoxin 2 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | 20 (best 0.73) |
| 7KIZ | Reduced human peroxiredoxin 2 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 7KJ0 | Hyperoxidized human peroxiredoxin 2 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 7KJ1 | human peroxiredoxin 2 - C172S mutant | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | 20 (best 0.73) |
| 7KJ1 | Human peroxiredoxin 2 - C172S mutant | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| P32119 | AlphaFold monomer V2.0 prediction for peroxiredoxin-2 (P32119) | — | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 5B8B chain F against the predicted model P0AE08: TM-score 0.99, RMSD 0.37 Å
- 5B8B chain G against the predicted model P0AE08: TM-score 0.99, RMSD 0.38 Å
- 5B8B chain J against the predicted model P0AE08: TM-score 0.99, RMSD 0.40 Å
- 5B8B chain H against the predicted model P0AE08: TM-score 0.99, RMSD 0.40 Å
- 5B8B chain C against the predicted model P0AE08: TM-score 0.99, RMSD 0.41 Å
- 5B8B chain B against the predicted model P0AE08: TM-score 0.99, RMSD 0.42 Å
- 5B8B chain I against the predicted model P0AE08: TM-score 0.99, RMSD 0.42 Å
- 5B8B chain D against the predicted model P0AE08: TM-score 0.99, RMSD 0.45 Å
- 5B8B chain E against the predicted model P0AE08: TM-score 0.99, RMSD 0.65 Å
- 5B8B chain A against the predicted model P0AE08: TM-score 0.99, RMSD 0.64 Å
Elsewhere
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