UniProt P31994
Low affinity immunoglobulin gamma Fc region receptor II-b (P31994)
Low affinity immunoglobulin gamma Fc region receptor II-b (UniProt P31994): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P31994
- Protein
- Low affinity immunoglobulin gamma Fc region receptor II-b
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of P31994 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FCB | Human Fc gamma receptor iib ectodomain (CD32) | x-ray diffraction | A | — | — |
| 2FCB | Human Fc gamma receptor iib ectodomain (CD32) | x-ray diffraction | A | — | — |
| 3WJJ | Crystal structure of IIb selective Fc variant, Fc(P238D), in complex with FcgRIIb | x-ray diffraction | C | — | — |
| 3WJJ | Crystal structure of iib selective Fc variant, FC(P238D), in complex with fcgriib | x-ray diffraction | C | — | — |
| 5OCC | Crystal structure of CD32b (Fc Gamma Receptor IIb) in complex with Human IgG1 Fab fragment (6G08) | x-ray diffraction | A | NAG, PO4 | 2 (best 0.80) |
| 5OCC | Crystal structure of CD32B (Fc gamma receptor iib) in complex with human IGG1 Fab fragment (6G08) | x-ray diffraction | A | NAG, PO4 | — |
| P31994 | AlphaFold monomer V2.0 prediction for low affinity immunoglobulin gamma Fc region receptor II-B… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5OCC chain A against the predicted model P31994: TM-score 0.98, RMSD 0.87 Å
- 5OCC chain A against the predicted model P31994: TM-score 0.98, RMSD 0.87 Å
- 3WJJ chain C against the predicted model P31994: TM-score 0.96, RMSD 1.52 Å
- 3WJJ chain C against the predicted model P31994: TM-score 0.96, RMSD 1.52 Å
- 2FCB chain A against the predicted model P31994: TM-score 0.94, RMSD 1.64 Å
- 2FCB chain A against the predicted model P31994: TM-score 0.94, RMSD 1.64 Å
Elsewhere
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