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UniProt P30878

Melibiose carrier protein (P30878)

Melibiose carrier protein (UniProt P30878): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P30878
Protein
Melibiose carrier protein
Experimental structures
8
Predicted models
1
Ligands
3
Pockets
11 · 4 records with a druggable one

Structures

9 records of P30878 in the MolNFT archive: 8 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4M643D crystal structure of Na+/melibiose symporter of Salmonella typhimuriumx-ray diffractionA, B, C, D——
4M643D crystal structure of NA+/MELIBIOSE symporter of salmonella typhimuriumx-ray diffractionA, B, C, D——
7L16Crystal structure of sugar-bound melibiose permease MelBx-ray diffractionALMO2 (best 0.83)
7L16Crystal structure of sugar-bound melibiose permease melbx-ray diffractionALMO—
7L17Crystal structure of sugar-bound melibiose permease MelBx-ray diffractionA9PG2 (best 0.83)
7L17Crystal structure of sugar-bound melibiose permease melbx-ray diffractionA9PG—
8FQ9Crystal structure of a ligand-bound cation-site mutant D55C of a melibiose transporterx-ray diffractionALMO2 (best 0.84)
8T60CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformationelectron microscopyANA5 (best 0.83)
P30878AlphaFold monomer V2.0 prediction for melibiose carrier protein (P30878)predictedA——

Ligands

  • LMO · dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside · in 3 records
  • 9PG · 4-nitrophenyl alpha-D-galactopyranoside · in 2 records
  • NA · Sodium ion · in 1 record

Experiment against prediction

Elsewhere

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