UniProt P30556
Type-1 angiotensin II receptor,Soluble cytochrome b562 BRIL fusion protein (P30556)
Type-1 angiotensin II receptor,Soluble cytochrome b562 BRIL fusion protein (UniProt P30556): 14 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 55 pockets. Binding sites, druggability and experiment…
- UniProt
- P30556
- Protein
- Type-1 angiotensin II receptor,Soluble cytochrome b562 BRIL fusion protein
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 55 · 8 records with a druggable one
Structures
15 records of P30556 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YAY | XFEL structure of human Angiotensin Receptor | x-ray diffraction | A | ZD7 | 6 (best 0.82) |
| 4YAY | Xfel structure of human angiotensin receptor | x-ray diffraction | A | — | — |
| 4ZUD | Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A… | x-ray diffraction | A | OLM | 5 (best 0.83) |
| 4ZUD | Crystal structure of human angiotensin receptor in complex with inverse agonist olmesartan at 2.8A… | x-ray diffraction | A | — | — |
| 6DO1 | Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8 | x-ray diffraction | A, B | NAG, CL | 14 (best 0.67) |
| 6DO1 | Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8 | x-ray diffraction | A, B | NAG, CL | — |
| 6OS0 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II | x-ray diffraction | A | NAG, CL | 4 (best 0.75) |
| 6OS0 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II | x-ray diffraction | A | NAG, CL | — |
| 6OS1 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023 | x-ray diffraction | A | CLR | 6 (best 0.69) |
| 6OS1 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023 | x-ray diffraction | A | CLR | — |
| 6OS2 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026 | x-ray diffraction | A | NAG, CLR | 6 (best 0.70) |
| 6OS2 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026 | x-ray diffraction | A | NH2, NAG, CLR | — |
| 8TH3 | Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor | electron microscopy | A, B | Y01 | 6 (best 0.81) |
| 8TH4 | Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and… | electron microscopy | A | LSN | 8 (best 0.85) |
| P30556 | AlphaFold monomer V2.0 prediction for type-1 angiotensin II receptor (P30556) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
- CL · Chloride ion · in 4 records
- CLR · Cholesterol · in 4 records
- LSN · [2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol · in 1 record
- NH2 · Amino group · in 1 record
- OLM · Olmesartan · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
- ZD7 · 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one · in 1 record
Experiment against prediction
- 6DO1 chain B against the predicted model P30556: TM-score 0.90, RMSD 2.39 Å
- 6DO1 chain B against the predicted model P30556: TM-score 0.90, RMSD 2.39 Å
- 6DO1 chain A against the predicted model P30556: TM-score 0.90, RMSD 2.38 Å
- 6DO1 chain A against the predicted model P30556: TM-score 0.90, RMSD 2.38 Å
- 8TH3 chain A against the predicted model P30556: TM-score 0.73, RMSD 1.60 Å
- 4YAY chain A against the predicted model P0ABE7: TM-score 0.26, RMSD 0.92 Å
- 4YAY chain A against the predicted model P0ABE7: TM-score 0.26, RMSD 0.92 Å
- 4ZUD chain A against the predicted model P0ABE7: TM-score 0.27, RMSD 0.92 Å
- 4ZUD chain A against the predicted model P0ABE7: TM-score 0.27, RMSD 0.92 Å
- 6OS1 chain A against the predicted model P30556: TM-score 0.73, RMSD 2.55 Å
Elsewhere
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