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UniProt P30530

Tyrosine-protein kinase receptor UFO (P30530)

Tyrosine-protein kinase receptor UFO (UniProt P30530), EC 2.7.10.1: 8 experimental structures on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P30530
Protein
Tyrosine-protein kinase receptor UFO
EC
2.7.10.1
Experimental structures
8
Predicted models
0
Ligands
2
Pockets
13 · 1 record with a druggable one

Structures

8 records of P30530 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2C5DStructure of a minimal Gas6-Axl complexx-ray diffractionC, D——
2C5DStructure of a minimal GAS6-axl complexx-ray diffractionC, D——
4RA0An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axisx-ray diffractionC, D——
4RA0An engineered axl 'decoy receptor' effectively silences the GAS6-axl signaling axisx-ray diffractionC, D——
5U6BStructure of the Axl kinase domain in complex with a macrocyclic inhibitorx-ray diffractionA, B, C, D7YS13 (best 0.77)
5U6BStructure of the axl kinase domain in complex with a macrocyclic inhibitorx-ray diffractionA, B, C, D7YS—
5VXZHigh-affinity axl decoy receptorx-ray diffractionC, DNAG—
P30530AlphaFold monomer V2.0 prediction for tyrosine-protein kinase receptor ufo (P30530)———

Ligands

  • 7YS · (10R)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3, 10,16-trimethyl-16,17-dihydro-1H-8,4-(azeno) pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record

Elsewhere

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