UniProt P30273
High affinity immunoglobulin epsilon receptor subunit gamma (P30273)
High affinity immunoglobulin epsilon receptor subunit gamma (UniProt P30273): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- P30273
- Protein
- High affinity immunoglobulin epsilon receptor subunit gamma
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 3 records with a druggable one
Structures
4 records of P30273 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Q5T | The tandem SH2 domains of SYK with a bound FCER1G diphospho-ITAM peptide | x-ray diffraction | GGG, HHH, III, JJJ, KKK, LLL | PO4 | 10 (best 0.78) |
| 8YVU | structure of Ige receptor | electron microscopy | C, D, G, H | CLR | 6 (best 0.71) |
| 8YWA | The structure of IgE receptor binding to IgE | electron microscopy | D, C | — | 1 (best 0.71) |
| P30273 | AlphaFold monomer V2.0 prediction for high affinity immunoglobulin epsilon receptor subunit gamma… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8YWA chain C against the predicted model P30273: TM-score 0.91, RMSD 0.47 Å
- 8YVU chain H against the predicted model P30273: TM-score 0.82, RMSD 1.04 Å
- 8YVU chain D against the predicted model P30273: TM-score 0.77, RMSD 1.18 Å
- 8YVU chain G against the predicted model P30273: TM-score 0.77, RMSD 0.77 Å
- 8YVU chain C against the predicted model P30273: TM-score 0.76, RMSD 0.85 Å
- 8YWA chain D against the predicted model P30273: TM-score 0.70, RMSD 1.36 Å
- 7Q5T chain KKK against the predicted model P30273: TM-score 0.23, RMSD 2.74 Å
- 7Q5T chain III against the predicted model P30273: TM-score 0.22, RMSD 1.90 Å
- 7Q5T chain LLL against the predicted model P30273: TM-score 0.22, RMSD 0.54 Å
- 7Q5T chain GGG against the predicted model P30273: TM-score 0.20, RMSD 2.60 Å
Elsewhere
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