UniProt P30050
60S ribosomal protein L12 (P30050)
60S ribosomal protein L12 (UniProt P30050): 48 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P30050
- Protein
- 60S ribosomal protein L12
- Experimental structures
- 48
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
49 records of P30050 in the MolNFT archive: 48 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V6X | Structure of the human 80S ribosome | electron microscopy | CK | — | — |
| 5A8L | Human eRF1 and the hCMV nascent peptide in the translation termination complex | electron microscopy | G | — | — |
| 5A8L | Human ERF1 and the hcmv nascent peptide in the translation termination complex | electron microscopy | G | — | — |
| 6OLG | Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) | electron microscopy | Aq | — | — |
| 6ZM7 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | electron microscopy | Lt | — | — |
| 6ZME | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | electron microscopy | Lt | — | — |
| 6ZMI | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | electron microscopy | Lt | — | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | Lt | — | — |
| 7VB2 | Solution structure of human ribosomal protein uL11 | solution nmr | A | — | — |
| 7VB2 | Solution structure of human ribosomal protein UL11 | solution nmr | A | — | — |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | BA | — | — |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | BA | — | — |
| 8FKT | Human nucleolar pre-60S ribosomal subunit (State C1) | electron microscopy | BA | — | — |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | BA | — | — |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | BA | — | — |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | BA | — | — |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | BA | — | — |
| 8FKY | Human nucleolar pre-60S ribosomal subunit (State F) | electron microscopy | BA | — | — |
| 8FKZ | Human nucleolar pre-60S ribosomal subunit (State G) | electron microscopy | BA | — | — |
| 8FL0 | Human nucleolar pre-60S ribosomal subunit (State H) | electron microscopy | BA | — | — |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | BA | — | — |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | BA | — | — |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | BA | — | — |
| 8FL6 | Human nuclear pre-60S ribosomal subunit (State J1) | electron microscopy | BA | — | — |
| 8FL7 | Human nuclear pre-60S ribosomal subunit (State J2) | electron microscopy | BA | — | — |
| 8FL9 | Human nuclear pre-60S ribosomal subunit (State J3) | electron microscopy | BA | — | — |
| 8FLA | Human nuclear pre-60S ribosomal subunit (State K1) | electron microscopy | BA | — | — |
| 8FLB | Human nuclear pre-60S ribosomal subunit (State K2) | electron microscopy | BA | — | — |
| 8FLC | Human nuclear pre-60S ribosomal subunit (State K3) | electron microscopy | BA | — | — |
| 8G5Z | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | electron microscopy | LK | — | — |
| 8G60 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | electron microscopy | LK | — | — |
| 8G6J | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) | electron microscopy | LK | — | — |
| 8IDT | human nuclear pre-60S ribosomal particle - State G | electron microscopy | y | — | — |
| 8IDY | human nuclear pre-60S ribosomal particle - State F | electron microscopy | y | — | — |
| 8INE | human nuclear pre-60S ribosomal particle - State G' | electron microscopy | y | — | — |
| 8INF | human nuclear pre-60S ribosomal particle - State F' | electron microscopy | y | — | — |
| 8INK | human nuclear pre-60S ribosomal particle - State D | electron microscopy | y | — | — |
| 8IPD | human nuclear pre-60S ribosomal particle - State C | electron microscopy | y | — | — |
| 8IPX | human nuclear pre-60S ribosomal particle - State C' | electron microscopy | y | — | — |
| 8IPY | human nuclear pre-60S ribosomal particle - State D' | electron microscopy | y | — | — |
| 8IR1 | human nuclear pre-60S ribosomal particle - State A | electron microscopy | y | — | 1 (best 0.84) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | y | — | — |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | Lt | — | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | LK | — | — |
| 8XSY | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head… | electron microscopy | Lt | — | — |
| 8XSZ | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | electron microscopy | Lt | — | — |
| 8YOO | Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | electron microscopy | Lt | — | — |
| 8YOP | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | electron microscopy | Lt | — | — |
| P30050 | AlphaFold monomer V2.0 prediction for 60S ribosomal protein L12 (P30050) | predicted | A | — | 1 (best 0.40) |
Experiment against prediction
- 8FL7 chain BA against the predicted model P30050: TM-score 0.96, RMSD 1.06 Å
- 8FL6 chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.09 Å
- 8FKR chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.08 Å
- 8FL9 chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.10 Å
- 8FL2 chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.13 Å
- 8FKS chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.11 Å
- 8FKT chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.15 Å
- 8FKU chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.15 Å
- 8FKX chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.15 Å
- 8FKV chain BA against the predicted model P30050: TM-score 0.95, RMSD 1.15 Å
Elsewhere
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