UniProt P29275
Adenosine A2b receptor (P29275)
Adenosine A2b receptor (UniProt P29275): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P29275
- Protein
- Adenosine A2b receptor
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 19 · 4 records with a druggable one
Structures
5 records of P29275 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XY6 | Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM | electron microscopy | R | I5D | 5 (best 0.77) |
| 7XY7 | Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM | electron microscopy | R | NEC | 5 (best 0.73) |
| 8HDO | Structure of A2BR bound to synthetic agonists BAY 60-6583 | electron microscopy | R | CLR, I5D | 5 (best 0.78) |
| 8HDP | Structure of A2BR bound to endogenous agonists adenosine | electron microscopy | R | ADN, CLR | 4 (best 0.80) |
| P29275 | AlphaFold monomer V2.0 prediction for adenosine receptor A2B (P29275) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8HDO chain R against the predicted model P29275: TM-score 0.90, RMSD 2.21 Å
- 7XY6 chain R against the predicted model P29275: TM-score 0.89, RMSD 2.40 Å
- 7XY7 chain R against the predicted model P29275: TM-score 0.89, RMSD 2.39 Å
- 8HDP chain R against the predicted model P29275: TM-score 0.88, RMSD 2.48 Å
- 7XY6 chain R against the predicted model P0ABE7: TM-score 0.26, RMSD 4.46 Å
- 7XY7 chain R against the predicted model P0ABE7: TM-score 0.26, RMSD 4.46 Å
Elsewhere
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