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UniProt P28700

Retinoic acid receptor RXR-alpha (P28700)

Retinoic acid receptor RXR-alpha (UniProt P28700): 13 experimental structures on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P28700
Protein
Retinoic acid receptor RXR-alpha
Experimental structures
13
Predicted models
0
Ligands
3
Pockets
13 · 3 records with a druggable one

Structures

13 records of P28700 in the MolNFT archive: 13 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1DKFCrystal structure of a heterodimeric complex of rar and rxr ligand-binding domainsx-ray diffractionA——
1DKFCrystal structure of a heterodimeric complex of rar and rxr ligand- binding domainsx-ray diffractionA——
1XDKCrystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis…x-ray diffractionA, E——
1XDKCrystal structure of the RARBETA/RXRALPHA ligand binding domain heterodimer in complex with 9-cis…x-ray diffractionA, E——
3A9ECrystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer…x-ray diffractionA——
3A9ECrystal structure of a mixed agonist-bound rar-alpha and antagonist- bound rxr-alpha heterodimer…x-ray diffractionA——
7AOScrystal structure of the RARalpha/RXRalpha ligand binding domain heterodimer in complex with a…x-ray diffractionALG26 (best 0.84)
7AOSCrystal structure of the RARALPHA/RXRALPHA ligand binding domain heterodimer in complex with a…x-ray diffractionALG2—
7PDQCrystal structure of a mutated form of RXRalpha ligand binding domain in complex with LG100268 and…x-ray diffractionALG22 (best 0.80)
7PDQCrystal structure of a mutated form of rxralpha ligand binding domain in complex with LG100268 and…x-ray diffractionALG2—
7PDTCrystal structure of a mutated form of rxralpha ligand binding domain in complex with BMS649 and a…x-ray diffractionA, BBM6—
7QAACrystal structure of RARalpha/RXRalpha ligand binding domain heterodimer in complex with BMS614 and…x-ray diffractionAOLA5 (best 0.85)
P28700AlphaFold monomer V2.0 prediction for retinoic acid receptor rxr- alpha (P28700)———

Ligands

  • LG2 · 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid · in 4 records
  • BM6 · 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[1,3]dioxolan-2-yl]-benzoic acid · in 1 record
  • OLA · Oleic acid · in 1 record

Elsewhere

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