UniProt P28330
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (P28330)
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (UniProt P28330), EC 1.3.8.8: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 58 pockets. Binding sites, druggability and experiment against…
- UniProt
- P28330
- Protein
- Long-chain specific acyl-CoA dehydrogenase, mitochondrial
- EC
- 1.3.8.8
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 58 · 3 records with a druggable one
Structures
4 records of P28330 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8W0T | Human LCAD | x-ray diffraction | A, B, C, D | FAD | 20 (best 0.88) |
| 8W0U | Human LCAD complexed with Acetoacetyl Coenzyme A | x-ray diffraction | A, B, C, D | FAD, CAA | 18 (best 0.88) |
| 8W0Z | Human LCAD complexed with Lauric Acid | x-ray diffraction | A, B, C, D, E, F, G, H | FAD, DAO | 20 (best 0.89) |
| P28330 | AlphaFold monomer V2.0 prediction for long-chain specific acyl-CoA dehydrogenase, mitochondrial… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8W0U chain A against the predicted model P28330: TM-score 1.00, RMSD 0.46 Å
- 8W0T chain D against the predicted model P28330: TM-score 1.00, RMSD 0.48 Å
- 8W0Z chain A against the predicted model P28330: TM-score 1.00, RMSD 0.50 Å
- 8W0Z chain G against the predicted model P28330: TM-score 1.00, RMSD 0.50 Å
- 8W0U chain B against the predicted model P28330: TM-score 1.00, RMSD 0.50 Å
- 8W0Z chain H against the predicted model P28330: TM-score 1.00, RMSD 0.51 Å
- 8W0T chain C against the predicted model P28330: TM-score 1.00, RMSD 0.51 Å
- 8W0Z chain B against the predicted model P28330: TM-score 0.99, RMSD 0.53 Å
- 8W0Z chain C against the predicted model P28330: TM-score 0.99, RMSD 0.53 Å
- 8W0Z chain F against the predicted model P28330: TM-score 0.99, RMSD 0.54 Å
Elsewhere
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