UniProt P28161
Glutathione S-transferase Mu 2 (P28161)
Glutathione S-transferase Mu 2 (UniProt P28161), EC 2.5.1.18: 22 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P28161
- Protein
- Glutathione S-transferase Mu 2
- EC
- 2.5.1.18
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
23 records of P28161 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HNA | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A | — | — |
| 1HNA | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A | — | — |
| 1HNB | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A, B | — | — |
| 1HNB | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A, B | — | — |
| 1HNC | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A, B, C, D | — | — |
| 1HNC | Crystal structure of human class mu glutathione transferase GSTM2-2: effects of lattice packing on… | x-ray diffraction | A, B, C, D | — | — |
| 1XW5 | Human glutathione s-transferase M2-2 (E.C.2.5.1.18)complexed with glutathione, monoclinic crystal… | x-ray diffraction | A, B | — | — |
| 1XW5 | Human glutathione S-transferase M2-2 (E.C.2.5.1.18)COMPLEXED with glutathione, monoclinic crystal… | x-ray diffraction | A, B | — | — |
| 1YKC | human glutathione S-transferase m2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide | x-ray diffraction | A, B | — | — |
| 1YKC | Human glutathione S-transferase M2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide | x-ray diffraction | A, B | — | — |
| 2AB6 | HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) complexed with S-METHYLGLUTATHIONE | x-ray diffraction | A, B, C, D | — | — |
| 2AB6 | Human glutathione S-transferase M2-2 (E.C.2.5.1.18) complexed with S- methylglutathione | x-ray diffraction | A, B, C, D | — | — |
| 2C4J | Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide… | x-ray diffraction | A, B, C, D | — | — |
| 2C4J | Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide… | x-ray diffraction | A, B, C, D | — | — |
| 2GTU | Ligand-free human glutathione S-transferase M2-2 (E.C.2.5.1.18), monoclinic crystal form | x-ray diffraction | A, B | — | — |
| 2GTU | Ligand-free human glutathione S-transferase M2-2 (E.C.2.5.1.18), monoclinic crystal form | x-ray diffraction | A, B | — | — |
| 3GTU | Ligand-free heterodimeric human glutathione S-transferase M2-3 (ec 2.5.1.18), monoclinic crystal… | x-ray diffraction | A, C | — | — |
| 3GTU | Ligand-free heterodimeric human glutathione S-transferase M2-3 (ec 2.5.1.18), monoclinic crystal… | x-ray diffraction | A, C | — | — |
| 3GUR | Crystal Structure of mu class glutathione S-transferase (GSTM2-2) in complex with glutathione and… | x-ray diffraction | A, B, C, D | — | — |
| 3GUR | Crystal structure of mu class glutathione S-transferase (GSTM2-2) in complex with glutathione and… | x-ray diffraction | A, B, C, D | — | — |
| 5HWL | Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form | x-ray diffraction | A, B | GSH, NNE | 2 (best 0.75) |
| 5HWL | Human glutathione S-transferase MU2 complexed with bdea, monoclinic crystal form | x-ray diffraction | A, B | — | — |
| P28161 | AlphaFold monomer V2.0 prediction for glutathione S-transferase mu 2 (P28161) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2AB6 chain A against the predicted model P28161: TM-score 1.00, RMSD 0.33 Å
- 2AB6 chain A against the predicted model P28161: TM-score 1.00, RMSD 0.33 Å
- 1XW5 chain A against the predicted model P28161: TM-score 1.00, RMSD 0.36 Å
- 1XW5 chain A against the predicted model P28161: TM-score 1.00, RMSD 0.36 Å
- 1YKC chain A against the predicted model P28161: TM-score 1.00, RMSD 0.37 Å
- 1YKC chain A against the predicted model P28161: TM-score 1.00, RMSD 0.37 Å
- 5HWL chain B against the predicted model P28161: TM-score 0.99, RMSD 0.40 Å
- 5HWL chain B against the predicted model P28161: TM-score 0.99, RMSD 0.40 Å
- 3GUR chain A against the predicted model P28161: TM-score 0.99, RMSD 0.42 Å
- 3GUR chain A against the predicted model P28161: TM-score 0.99, RMSD 0.42 Å
Elsewhere
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