UniProt P28063
Proteasome subunit beta type-8,Proteasome subunit beta type-5 (P28063)
Proteasome subunit beta type-8,Proteasome subunit beta type-5 (UniProt P28063), EC 3.4.25.1: 19 experimental structures on GenesisL1, 9 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P28063
- Protein
- Proteasome subunit beta type-8,Proteasome subunit beta type-5
- EC
- 3.4.25.1
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 10 · 3 records with a druggable one
Structures
19 records of P28063 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3UNH | Mouse 20S immunoproteasome | x-ray diffraction | K, Y | — | — |
| 3UNH | Mouse 20S immunoproteasome | x-ray diffraction | K, Y | — | — |
| 5L65 | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 3BV | — |
| 5L65 | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 3BV | — |
| 5L66 | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, BO2 | 3 (best 0.78) |
| 5L66 | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, BO2 | — |
| 5L67 | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 39V | 3 (best 0.78) |
| 5L67 | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 39V | — |
| 5L68 | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 6N5 | — |
| 5L68 | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 6N5 | — |
| 5L69 | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 79P | 4 (best 0.78) |
| 5L69 | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 79P | — |
| 5L6A | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 79L | — |
| 5L6A | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 79L | — |
| 5L6B | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 04C | — |
| 5L6B | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 04C | — |
| 5L6C | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 6NV | — |
| 5L6C | Yeast 20S proteasome with mouse BETA5I (1-138) and mouse BETA6 (97- 111; 118-133) in complex with… | x-ray diffraction | K, Y | MG, 6NV | — |
| P28063 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-8 (P28063) | — | — | — |
Ligands
- MG · Magnesium ion · in 16 records
- 04C · 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol · in 2 records
- 39V · N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S, 4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide · in 2 records
- 3BV · N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide · in 2 records
- 6N5 · ~{N}-[(2~{S})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide · in 2 records
- 6NV · ~{N}-[(2~{R})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide · in 2 records
- 79L · (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide · in 2 records
- 79P · (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide · in 2 records
- BO2 · N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide · in 2 records
Elsewhere
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