UniProt P28039
Acyloxyacyl hydrolase (P28039)
Acyloxyacyl hydrolase (UniProt P28039), EC 3.1.1.77: 3 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P28039
- Protein
- Acyloxyacyl hydrolase
- EC
- 3.1.1.77
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 11 · 1 record with a druggable one
Structures
4 records of P28039 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5W78 | Human acyloxyacyl hydrolase (aoah), proteolytically processed | x-ray diffraction | A, B | NAG, MYR, CA, PLM, DAO | — |
| 5W7C | Human acyloxyacyl hydrolase (AOAH), proteolytically processed, S263A mutant, with LPS | x-ray diffraction | A, C, B, D | NAG, FTT, CA, DAO | 11 (best 0.78) |
| 5W7C | Human acyloxyacyl hydrolase (aoah), proteolytically processed, S263A mutant, with lps | x-ray diffraction | A, C, B, D | NAG, FTT, CA, DAO | — |
| P28039 | AlphaFold monomer V2.0 prediction for acyloxyacyl hydrolase (P28039) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5W7C chain C against the predicted model P28039: TM-score 0.98, RMSD 1.17 Å
- 5W7C chain C against the predicted model P28039: TM-score 0.98, RMSD 1.17 Å
- 5W7C chain D against the predicted model P28039: TM-score 0.98, RMSD 1.19 Å
- 5W7C chain D against the predicted model P28039: TM-score 0.98, RMSD 1.19 Å
- 5W78 chain B against the predicted model P28039: TM-score 0.97, RMSD 1.83 Å
- 5W7C chain B against the predicted model P28039: TM-score 0.95, RMSD 1.46 Å
- 5W7C chain B against the predicted model P28039: TM-score 0.95, RMSD 1.46 Å
- 5W7C chain A against the predicted model P28039: TM-score 0.95, RMSD 1.42 Å
- 5W7C chain A against the predicted model P28039: TM-score 0.95, RMSD 1.42 Å
- 5W78 chain A against the predicted model P28039: TM-score 0.92, RMSD 1.42 Å
Elsewhere
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