UniProt P27782
Lymphoid enhancer-binding factor 1 (P27782)
Lymphoid enhancer-binding factor 1 (UniProt P27782): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P27782
- Protein
- Lymphoid enhancer-binding factor 1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
7 records of P27782 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LEF | LEF1 hmg domain (from mouse), complexed with DNA (15BP), NMR, 12 structures | solution nmr | A | — | — |
| 2LEF | LEF1 hmg domain (from mouse), complexed with DNA (15BP), NMR, 12 structures | solution nmr | A | — | — |
| 3OUW | Structure of beta-catenin with Lef-1 | x-ray diffraction | B | — | — |
| 3OUW | Structure of beta-catenin with lef-1 | x-ray diffraction | B | — | — |
| 3OUX | Structure of beta-catenin with phosphorylated Lef-1 | x-ray diffraction | B | — | — |
| 3OUX | Structure of beta-catenin with phosphorylated lef-1 | x-ray diffraction | B | — | — |
| P27782 | AlphaFold monomer V2.0 prediction for lymphoid enhancer-binding factor 1 (P27782) | predicted | A | — | 2 (best 0.34) |
Experiment against prediction
- 2LEF chain A against the predicted model P27782: TM-score 0.81, RMSD 2.03 Å
- 2LEF chain A against the predicted model P27782: TM-score 0.81, RMSD 2.03 Å
- 3OUX chain B against the predicted model P27782: TM-score 0.27, RMSD 3.66 Å
- 3OUX chain B against the predicted model P27782: TM-score 0.27, RMSD 3.66 Å
- 3OUW chain B against the predicted model P27782: TM-score 0.25, RMSD 3.23 Å
- 3OUW chain B against the predicted model P27782: TM-score 0.25, RMSD 3.23 Å
Elsewhere
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