UniProt P27090
Transforming growth factor beta-2 (P27090)
Transforming growth factor beta-2 (UniProt P27090): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P27090
- Protein
- Transforming growth factor beta-2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
4 records of P27090 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TX2 | Miniature TGF-BETA2 3-mutant monomer | x-ray diffraction | A, B | — | — |
| 5TX6 | Structure of TGF-beta2 derivative with deletion of residues 52-71 and 10 single amino acid… | x-ray diffraction | B, A, C | CA | 2 (best 0.43) |
| 5TX6 | Structure of TGF-BETA2 derivative with deletion of residues 52-71 and 10 single amino acid… | x-ray diffraction | B, A, C | CA | — |
| P27090 | AlphaFold monomer V2.0 prediction for transforming growth factor beta-2 proprotein (P27090) | predicted | A | — | 6 (best 0.60) |
Ligands
- CA · Calcium ion · in 2 records
Experiment against prediction
- 5TX6 chain C against the predicted model P27090: TM-score 0.80, RMSD 2.01 Å
- 5TX6 chain C against the predicted model P27090: TM-score 0.80, RMSD 2.01 Å
- 5TX6 chain A against the predicted model P27090: TM-score 0.80, RMSD 2.34 Å
- 5TX6 chain A against the predicted model P27090: TM-score 0.80, RMSD 2.34 Å
- 5TX6 chain B against the predicted model P27090: TM-score 0.79, RMSD 2.53 Å
- 5TX6 chain B against the predicted model P27090: TM-score 0.79, RMSD 2.53 Å
- 5TX2 chain A against the predicted model P27090: TM-score 0.75, RMSD 2.49 Å
Elsewhere
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