UniProt P26285
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (P26285)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (UniProt P26285), EC 2.7.1.105, 3.1.3.46: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment…
- UniProt
- P26285
- Protein
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- EC
- 2.7.1.105, 3.1.3.46
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
3 records of P26285 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HR5 | Bovine Heart 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB2) | x-ray diffraction | A | F6P, ADP | 3 (best 0.81) |
| 5HR5 | Bovine heart 6-phosphofructo-2-KINASE/FRUCTOSE-2,6-bisphosphatase (PFKFB2) | x-ray diffraction | A | — | — |
| P26285 | AlphaFold monomer V2.0 prediction for 6-phosphofructo-2-KINASE/FRUCTOSE-2,6-bisphosphatase 2… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5HR5 chain A against the predicted model P26285: TM-score 0.99, RMSD 0.56 Å
- 5HR5 chain A against the predicted model P26285: TM-score 0.99, RMSD 0.56 Å
Elsewhere
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