UniProt P26010
Integrin beta-7 (P26010)
Integrin beta-7 (UniProt P26010): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P26010
- Protein
- Integrin beta-7
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 1 record with a druggable one
Structures
8 records of P26010 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BRQ | Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail… | x-ray diffraction | C, D | — | — |
| 2BRQ | Crystal structure of the filamin a repeat 21 complexed with the integrin BETA7 cytoplasmic tail… | x-ray diffraction | C, D | — | — |
| 3V4P | crystal structure of a4b7 headpiece complexed with Fab ACT-1 | x-ray diffraction | B, D | — | — |
| 3V4P | Crystal structure of A4B7 headpiece complexed with Fab act-1 | x-ray diffraction | B, D | — | — |
| 3V4V | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | x-ray diffraction | B, D | — | — |
| 3V4V | Crystal structure of A4B7 headpiece complexed with Fab act-1 and RO0505376 | x-ray diffraction | B, D | — | — |
| 8ZJF | Cryo-EM structure of human integrin alpha-E beta-7 | electron microscopy | B | MG, CA | 12 (best 0.82) |
| P26010 | AlphaFold monomer V2.0 prediction for integrin beta-7 (P26010) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3V4P chain B against the predicted model P26010: TM-score 0.98, RMSD 1.16 Å
- 3V4P chain B against the predicted model P26010: TM-score 0.98, RMSD 1.16 Å
- 3V4V chain B against the predicted model P26010: TM-score 0.98, RMSD 1.22 Å
- 3V4V chain B against the predicted model P26010: TM-score 0.98, RMSD 1.22 Å
- 8ZJF chain B against the predicted model P26010: TM-score 0.91, RMSD 2.18 Å
- 2BRQ chain C against the predicted model P26010: TM-score 0.41, RMSD 0.67 Å
- 2BRQ chain C against the predicted model P26010: TM-score 0.41, RMSD 0.67 Å
Elsewhere
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