UniProt P25519
GTPase HflX (P25519)
GTPase HflX (UniProt P25519): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P25519
- Protein
- GTPase HflX
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of P25519 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ADY | Cryo-EM structures of the 50S ribosome subunit bound with hflx | electron microscopy | 6 | — | — |
| 5ZZM | E. coli 50S subunit bound HflX protein in presence of ATP (AMP-PNP) and GTP (GMP-PNP) analogs. | electron microscopy | A | — | 1 (best 0.39) |
| 5ZZM | E. COLI 50S subunit bound hflx protein in presence of ATP (AMP-pnp) and GTP (gmp-pnp) analogs. | electron microscopy | A | — | — |
| 7YLA | Cryo-EM structure of 50S-HflX complex | electron microscopy | 6 | GNP, MG | 1 (best 0.86) |
| P25519 | AlphaFold monomer V2.0 prediction for GTPase hflx (P25519) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7YLA chain 6 against the predicted model P25519: TM-score 0.88, RMSD 2.83 Å
- 5ADY chain 6 against the predicted model P25519: TM-score 0.87, RMSD 3.12 Å
- 5ZZM chain A against the predicted model P25519: TM-score 0.74, RMSD 4.77 Å
- 5ZZM chain A against the predicted model P25519: TM-score 0.74, RMSD 4.77 Å
Elsewhere
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