UniProt P24481
Phenylalanine ammonia-lyase 1 (P24481)
Phenylalanine ammonia-lyase 1 (UniProt P24481), EC 4.3.1.24, 4.3.1.5: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 64 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P24481
- Protein
- Phenylalanine ammonia-lyase 1
- EC
- 4.3.1.24, 4.3.1.5
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 64 · 4 records with a druggable one
Structures
11 records of P24481 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W27 | Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum | x-ray diffraction | A, B | — | 18 (best 0.83) |
| 1W27 | Phenylalanine ammonia-lyase (pal) from petroselinum crispum | x-ray diffraction | A, B | — | — |
| 6F6T | Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum complexed with S-APPA | x-ray diffraction | A, B | CV2 | 18 (best 0.82) |
| 6F6T | Phenylalanine ammonia-lyase (pal) from petroselinum crispum complexed with S-appa | x-ray diffraction | A, B | CV2 | — |
| 6H2O | APO structure of Phenylalanine ammonia-lyase from Petroselinum crispum | x-ray diffraction | A, B | — | 19 (best 0.80) |
| 6H2O | Apo structure of phenylalanine ammonia-lyase from petroselinum crispum | x-ray diffraction | A, B | — | — |
| 6HQF | Structure of Phenylalanine ammonia-lyase from Petroselinum crispum in complex with (R)-APEP | x-ray diffraction | A, B | PPH | — |
| 6HQF | Structure of phenylalanine ammonia-lyase from petroselinum crispum in complex with (R)-apep | x-ray diffraction | A, B | PPH | — |
| 6RGS | Crystal Structure of Phenylalanine Ammonia Lyase (PAL) from Petroselinum crispum bound to cinnamate | x-ray diffraction | A, B | K3Z | — |
| 6RGS | Crystal structure of phenylalanine ammonia lyase (pal) from petroselinum crispum bound to cinnamate | x-ray diffraction | A, B | K3Z | — |
| P24481 | AlphaFold monomer V2.0 prediction for phenylalanine ammonia-lyase 1 (P24481) | predicted | A | — | 9 (best 0.59) |
Ligands
Experiment against prediction
- 6RGS chain A against the predicted model P24481: TM-score 0.99, RMSD 0.67 Å
- 6RGS chain A against the predicted model P24481: TM-score 0.99, RMSD 0.67 Å
- 6H2O chain A against the predicted model P24481: TM-score 0.99, RMSD 0.68 Å
- 6H2O chain A against the predicted model P24481: TM-score 0.99, RMSD 0.68 Å
- 6H2O chain B against the predicted model P24481: TM-score 0.99, RMSD 0.73 Å
- 6RGS chain B against the predicted model P24481: TM-score 0.99, RMSD 0.71 Å
- 6H2O chain B against the predicted model P24481: TM-score 0.99, RMSD 0.73 Å
- 6RGS chain B against the predicted model P24481: TM-score 0.99, RMSD 0.71 Å
- 6F6T chain B against the predicted model P24481: TM-score 0.99, RMSD 0.78 Å
- 6F6T chain B against the predicted model P24481: TM-score 0.99, RMSD 0.78 Å
Elsewhere
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