UniProt P23909
DNA mismatch repair protein MutS (P23909)
DNA mismatch repair protein MutS (UniProt P23909): 44 experimental structures on GenesisL1, 6 ligands bound, 44 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P23909
- Protein
- DNA mismatch repair protein MutS
- Experimental structures
- 44
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 44 · 3 records with a druggable one
Structures
44 records of P23909 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E3M | The crystal structure of E. coli MutS binding to DNA with a G:T mismatch | x-ray diffraction | A, B | — | — |
| 1E3M | The crystal structure of E. COLI muts binding to DNA with a G:T mismatch | x-ray diffraction | A, B | — | — |
| 1NG9 | E.coli MutS R697A: an ATPase-asymmetry mutant | x-ray diffraction | A, B | — | — |
| 1NG9 | E.COLI muts R697A: an ATPase-asymmetry mutant | x-ray diffraction | A, B | — | — |
| 1OH5 | The crystal structure of E. COLI muts binding to DNA with a C:A mismatch | x-ray diffraction | A, B | — | — |
| 1OH5 | The crystal structure of E. COLI muts binding to DNA with a C:A mismatch | x-ray diffraction | A, B | — | — |
| 1OH6 | The crystal structure of E. COLI muts binding to DNA with an A:A mismatch | x-ray diffraction | A, B | — | — |
| 1OH6 | The crystal structure of E. COLI muts binding to DNA with an A:A mismatch | x-ray diffraction | A, B | — | — |
| 1OH7 | The crystal structure of E. COLI muts binding to DNA with a G:G mismatch | x-ray diffraction | A, B | — | — |
| 1OH7 | The crystal structure of E. COLI muts binding to DNA with a G:G mismatch | x-ray diffraction | A, B | — | — |
| 1OH8 | The crystal structure of E. COLI muts binding to DNA with an unpaired thymidine | x-ray diffraction | A, B | — | — |
| 1OH8 | The crystal structure of E. COLI muts binding to DNA with an unpaired thymidine | x-ray diffraction | A, B | — | — |
| 1W7A | ATP bound MutS | x-ray diffraction | A, B | — | — |
| 1W7A | ATP bound muts | x-ray diffraction | A, B | — | — |
| 1WB9 | Crystal Structure of E. coli DNA Mismatch Repair enzyme MutS, E38T mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 1WB9 | Crystal structure of E. COLI DNA mismatch repair enzyme muts, E38T mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 1WBB | Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38A mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 1WBB | Crystal structure of E. COLI DNA mismatch repair enzyme muts, E38A mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 1WBD | Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38Q mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 1WBD | Crystal structure of E. COLI DNA mismatch repair enzyme muts, E38Q mutant, in complex with a G.T… | x-ray diffraction | A, B | — | — |
| 2OK2 | MutS C-terminal domain fused to Maltose Binding Protein | x-ray diffraction | A, B | — | — |
| 2OK2 | Muts C-terminal domain fused to maltose binding protein | x-ray diffraction | A, B | — | — |
| 2WTU | Crystal structure of Escherichia coli MutS in complex with a 16 basepair oligo containing an A.A… | x-ray diffraction | A, B | — | — |
| 2WTU | Crystal structure of escherichia COLI muts in complex with a 16 basepair oligo containing an A.A… | x-ray diffraction | A, B | — | — |
| 3K0S | Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT… | x-ray diffraction | A, B | — | — |
| 3K0S | Crystal structure of E.COLI DNA mismatch repair protein muts, D693N mutant, in complex with gt… | x-ray diffraction | A, B | — | — |
| 3ZLJ | Crystal structure of full-length E.COLI DNA mismatch repair protein muts D835R mutant in complex… | x-ray diffraction | A, B, C, D | — | — |
| 3ZLJ | Crystal structure of full-length E.COLI DNA mismatch repair protein muts D835R mutant in complex… | x-ray diffraction | A, B, C, D | — | — |
| 5AKB | Muts in complex with the N-terminal domain of mutl - crystal form 1 | x-ray diffraction | A, B, E | — | — |
| 5AKC | MutS in complex with the N-terminal domain of MutL - crystal form 2 | x-ray diffraction | A, B, E, F, I, J | ANP | 16 (best 0.80) |
| 5AKC | Muts in complex with the N-terminal domain of mutl - crystal form 2 | x-ray diffraction | A, B, E, F, I, J | — | — |
| 5AKD | Muts in complex with the N-terminal domain of mutl - crystal form 3 | x-ray diffraction | A, B, E, F, I, J | — | — |
| 6I5F | Crystal structure of DNA-free E.coli MutS P839E dimer mutant | x-ray diffraction | A, B | SO4, ADP | — |
| 6I5F | Crystal structure of DNA-free E.COLI muts P839E dimer mutant | x-ray diffraction | A, B | SO4, ADP | — |
| 7AI6 | Muts in mismatch bound state | electron microscopy | A, B | ADP | — |
| 7AI7 | Muts in intermediate state | electron microscopy | A, B | ADP | — |
| 7AIB | Muts-mutl in clamp state | electron microscopy | A, B | ANP | — |
| 7AIC | MutS-MutL in clamp state (kinked clamp domain) | electron microscopy | A, B | ANP | 17 (best 0.82) |
| 7AIC | Muts-mutl in clamp state (kinked clamp domain) | electron microscopy | A, B | ANP | — |
| 7OTO | The structure of muts bound to two molecules of amppnp | electron microscopy | B, A | MG, ANP | — |
| 7OU0 | The structure of MutS bound to two molecules of ADP-Vanadate | electron microscopy | B, A | MG, ADP, VO4 | 11 (best 0.85) |
| 7OU0 | The structure of muts bound to two molecules of ADP-vanadate | electron microscopy | B, A | MG, ADP, VO4 | — |
| 7OU4 | The structure of muts bound to one molecule of ATP and one molecule of ADP | electron microscopy | A, B | MG, ATP, ADP | — |
| P23909 | AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P23909) | — | — | — |
Ligands
Experiment against prediction
- 2OK2 chain A against the predicted model P0AEX9: TM-score 0.92, RMSD 0.40 Å
Elsewhere
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