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UniProt P22304

Iduronate 2-sulfatase (P22304)

Iduronate 2-sulfatase (UniProt P22304), EC 3.1.6.13: 5 experimental structures on GenesisL1, 4 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P22304
Protein
Iduronate 2-sulfatase
EC
3.1.6.13
Experimental structures
5
Predicted models
0
Ligands
4
Pockets
4 · 1 record with a druggable one

Structures

5 records of P22304 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5FQLInsights into Hunter syndrome from the structure of iduronate-2- sulfatasex-ray diffractionANAG, FUC, CA, CL—
5FQLInsights into hunter syndrome from the structure of iduronate-2- sulfatasex-ray diffractionA——
6IOZStructural insights of idursulfase betax-ray diffractionANAG, FUC, CA4 (best 0.56)
6IOZStructural insights of idursulfase betax-ray diffractionANAG, FUC, CA—
P22304AlphaFold monomer V2.0 prediction for iduronate 2-sulfatase (P22304)———

Ligands

  • CA · Calcium ion · in 3 records
  • FUC · alpha-L-fucopyranose · in 3 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
  • CL · Chloride ion · in 1 record

Elsewhere

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