UniProt P22004
Bone morphogenetic protein 6 (P22004)
Bone morphogenetic protein 6 (UniProt P22004): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22004
- Protein
- Bone morphogenetic protein 6
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
9 records of P22004 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QCW | Crystal Structure of Bone Morphogenetic Protein-6 (BMP-6) | x-ray diffraction | A, B | — | — |
| 2QCW | Crystal structure of bone morphogenetic protein-6 (bmp-6) | x-ray diffraction | A, B | — | — |
| 2R52 | Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6) | x-ray diffraction | A, B | — | — |
| 2R52 | Crystal structure analysis of bone morphogenetic protein-6 (bmp-6) | x-ray diffraction | A, B | — | — |
| 2R53 | Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6) | x-ray diffraction | A, B | — | — |
| 2R53 | Crystal structure analysis of bone morphogenetic protein-6 variant B2 (B2-bmp-6) | x-ray diffraction | A, B | — | — |
| 6OMO | Human BMP6 homodimer | x-ray diffraction | I, J | NAG | 3 (best 0.44) |
| 6OMO | Human BMP6 homodimer | x-ray diffraction | I, J | NAG | — |
| P22004 | AlphaFold monomer V2.0 prediction for bone morphogenetic protein 6 (P22004) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 2R53 chain B against the predicted model P22004: TM-score 0.92, RMSD 1.19 Å
- 2R53 chain B against the predicted model P22004: TM-score 0.92, RMSD 1.19 Å
- 2QCW chain A against the predicted model P22004: TM-score 0.92, RMSD 1.18 Å
- 2QCW chain A against the predicted model P22004: TM-score 0.92, RMSD 1.18 Å
- 6OMO chain I against the predicted model P22004: TM-score 0.91, RMSD 1.24 Å
- 6OMO chain I against the predicted model P22004: TM-score 0.91, RMSD 1.24 Å
- 2R52 chain B against the predicted model P22004: TM-score 0.91, RMSD 1.23 Å
- 2R52 chain B against the predicted model P22004: TM-score 0.91, RMSD 1.23 Å
- 2QCW chain B against the predicted model P22004: TM-score 0.91, RMSD 1.83 Å
- 2QCW chain B against the predicted model P22004: TM-score 0.91, RMSD 1.83 Å
Elsewhere
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