UniProt P22001
Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion (P22001)
Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion (UniProt P22001): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 56 pockets. Binding sites, druggability and…
- UniProt
- P22001
- Protein
- Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein…
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 56 · 4 records with a druggable one
Structures
15 records of P22001 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BGC | T1 domain of the renal potassium channel Kv1.3 | x-ray diffraction | A | — | — |
| 4BGC | T1 domain of the renal potassium channel KV1.3 | x-ray diffraction | A | — | — |
| 7EJ1 | Human voltage-gated potassium channel KV1.3 | electron microscopy | B, D, F, H | — | — |
| 7EJ2 | Human voltage-gated potassium channel KV1.3 H451N mutant | electron microscopy | B, D, F, H | — | — |
| 7SSV | Structure of human Kv1.3 with Fab-ShK fusion | electron microscopy | A, B, C, D | K | 15 (best 0.83) |
| 7SSV | Structure of human KV1.3 with Fab-shk fusion | electron microscopy | A, B, C, D | K | — |
| 7SSX | Structure of human Kv1.3 | electron microscopy | A, B, C, D | K | 19 (best 0.84) |
| 7SSX | Structure of human KV1.3 | electron microscopy | A, B, C, D | K | — |
| 7SSY | Structure of human KV1.3 (alternate conformation) | electron microscopy | A, B, C, D | K | — |
| 7SSZ | Structure of human Kv1.3 with A0194009G09 nanobodies | electron microscopy | A, B, C, D | K | 20 (best 0.83) |
| 7SSZ | Structure of human KV1.3 with A0194009G09 nanobodies | electron microscopy | A, B, C, D | K | — |
| 7WF3 | Composite MAP of human KV1.3 channel in apo state with beta subunits | electron microscopy | B, D, F, H, J, N, O, P | K | — |
| 7WF4 | Composite MAP of human KV1.3 channel in dalazatide-bound state with beta subunits | electron microscopy | D, J, N, O, P, B, F, H | K | — |
| 8DFL | Structure of human KV1.3 with A0194009G09 nanobodies (alternate conformation) | electron microscopy | A, B, C, D | K | — |
| P22001 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily a member 3 (P22001) | predicted | A | — | 2 (best 0.74) |
Ligands
- K · Potassium ion · in 10 records
Experiment against prediction
- 4BGC chain A against the predicted model P22001: TM-score 0.97, RMSD 0.81 Å
- 4BGC chain A against the predicted model P22001: TM-score 0.97, RMSD 0.81 Å
- 7WF4 chain J against the predicted model P22001: TM-score 0.95, RMSD 1.29 Å
- 7EJ1 chain B against the predicted model P22001: TM-score 0.95, RMSD 1.77 Å
- 7WF3 chain J against the predicted model P22001: TM-score 0.95, RMSD 0.99 Å
- 7EJ2 chain B against the predicted model P22001: TM-score 0.95, RMSD 1.78 Å
- 7SSV chain A against the predicted model P22001: TM-score 0.95, RMSD 1.65 Å
- 7SSV chain A against the predicted model P22001: TM-score 0.95, RMSD 1.65 Å
- 7WF4 chain D against the predicted model P22001: TM-score 0.94, RMSD 1.55 Å
- 7WF3 chain B against the predicted model P22001: TM-score 0.94, RMSD 1.57 Å
Elsewhere
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