UniProt P21827
Guanine nucleotide exchange factor SRM1 (P21827)
Guanine nucleotide exchange factor SRM1 (UniProt P21827): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P21827
- Protein
- Guanine nucleotide exchange factor SRM1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of P21827 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3OF7 | The Crystal Structure of Prp20p from Saccharomyces cerevisiae and Its Binding Properties to Gsp1p… | x-ray diffraction | A | — | — |
| 3OF7 | The crystal structure of PRP20P from saccharomyces cerevisiae and its binding properties to GSP1P… | x-ray diffraction | A | — | — |
| 4OIH | Importin Alpha in Complex with the Bipartite NLS of Prp20 | x-ray diffraction | B | — | — |
| 4OIH | Importin alpha in complex with the bipartite nls of PRP20 | x-ray diffraction | B | — | — |
| 5HQ2 | Structural model of SET8 histone H4 LYS20 methyltransferase bound to nucleosome core particle | x-ray diffraction | K | — | — |
| 5T94 | Crystal structure of KAP60 bound to yeast RCC1 (PRP20) | x-ray diffraction | A | — | — |
| P21827 | AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SRM1 (P21827) | predicted | A | — | 2 (best 0.83) |
Experiment against prediction
- 3OF7 chain A against the predicted model P21827: TM-score 0.99, RMSD 0.71 Å
- 3OF7 chain A against the predicted model P21827: TM-score 0.99, RMSD 0.71 Å
- 5HQ2 chain K against the predicted model P21827: TM-score 0.97, RMSD 1.29 Å
- 5T94 chain A against the predicted model P21827: TM-score 0.96, RMSD 1.34 Å
- 4OIH chain B against the predicted model P21827: TM-score 0.32, RMSD 1.34 Å
- 4OIH chain B against the predicted model P21827: TM-score 0.32, RMSD 1.34 Å
Elsewhere
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