UniProt P21462
fMet-Leu-Phe receptor (P21462)
fMet-Leu-Phe receptor (UniProt P21462): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P21462
- Protein
- fMet-Leu-Phe receptor
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 3 records with a druggable one
Structures
7 records of P21462 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EUO | The structure of formyl peptide receptor 1 in complex with Gi and peptide agonist fMLF | electron microscopy | R | CLR | 7 (best 0.70) |
| 7EUO | The structure of formyl peptide receptor 1 in complex with gi and peptide agonist fmlf | electron microscopy | R | CLR | — |
| 7T6T | Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1… | electron microscopy | R | PLM | — |
| 7VFX | The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL | electron microscopy | R | CLR, PLM | 5 (best 0.71) |
| 7WVU | Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1 | electron microscopy | R | — | 4 (best 0.71) |
| 7WVU | Cryo-EM structure of the human formyl peptide receptor 1 in complex with fmlf and GI1 | electron microscopy | R | — | — |
| P21462 | AlphaFold monomer V2.0 prediction for fmet-leu-phe receptor (P21462) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7VFX chain R against the predicted model P21462: TM-score 0.95, RMSD 1.65 Å
- 7T6T chain R against the predicted model P21462: TM-score 0.95, RMSD 1.68 Å
- 7EUO chain R against the predicted model P21462: TM-score 0.95, RMSD 1.73 Å
- 7EUO chain R against the predicted model P21462: TM-score 0.95, RMSD 1.73 Å
- 7WVU chain R against the predicted model P21462: TM-score 0.94, RMSD 1.78 Å
- 7WVU chain R against the predicted model P21462: TM-score 0.94, RMSD 1.78 Å
Elsewhere
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