UniProt P21372
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (P21372)
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (UniProt P21372): 8 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P21372
- Protein
- Pre-mRNA-processing ATP-dependent RNA helicase PRP5
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 19 · 3 records with a druggable one
Structures
9 records of P21372 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4LJY | Crystal structure of RNA splicing effector Prp5 in complex with ADP | x-ray diffraction | A | — | — |
| 4LJY | Crystal structure of RNA splicing effector PRP5 in complex with ADP | x-ray diffraction | A | — | — |
| 4LK2 | Crystal structure of RNA splicing effector Prp5 | x-ray diffraction | A, B | — | — |
| 4LK2 | Crystal structure of RNA splicing effector PRP5 | x-ray diffraction | A, B | — | — |
| 7OQB | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | electron microscopy | p | — | 3 (best 0.82) |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | p | — | — |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | electron microscopy | p | — | 2 (best 0.82) |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | p | — | — |
| P21372 | AlphaFold monomer V2.0 prediction for pre-mRNA-processing ATP- dependent RNA helicase PRP5 (P21372) | predicted | A | — | 14 (best 0.68) |
Experiment against prediction
- 4LK2 chain B against the predicted model P21372: TM-score 0.60, RMSD 1.73 Å
- 4LK2 chain B against the predicted model P21372: TM-score 0.60, RMSD 1.73 Å
- 4LJY chain A against the predicted model P21372: TM-score 0.60, RMSD 1.43 Å
- 4LJY chain A against the predicted model P21372: TM-score 0.60, RMSD 1.43 Å
- 4LK2 chain A against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
- 4LK2 chain A against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
- 7OQE chain p against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
- 7OQE chain p against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
- 7OQB chain p against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
- 7OQB chain p against the predicted model P21372: TM-score 0.59, RMSD 1.69 Å
Elsewhere
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