UniProt P20292
P20292
P20292 (UniProt P20292): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20292
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
Structures
7 records of P20292 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Q7M | Crystal structure of human FLAP with MK-591 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Q7M | Crystal structure of human flap with mk-591 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Q7R | Crystal structure of human FLAP with an iodinated analog of MK-591 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2Q7R | Crystal structure of human flap with an iodinated analog of mk-591 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6VGC | Crystal structures of flap bound to dg-031 | x-ray diffraction | A, B, C, D, E, F | QY1, CA | — |
| 6VGI | Crystal structures of flap bound to mk-866 | x-ray diffraction | A, B, C, D, E, F | QY7, SO4 | — |
| P20292 | AlphaFold monomer V2.0 prediction for arachidonate 5-lipoxygenase- activating protein (P20292) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2Q7R chain A against the predicted model P20292: TM-score 0.91, RMSD 1.68 Å
- 2Q7R chain A against the predicted model P20292: TM-score 0.91, RMSD 1.68 Å
- 2Q7M chain E against the predicted model P20292: TM-score 0.91, RMSD 1.87 Å
- 2Q7M chain E against the predicted model P20292: TM-score 0.91, RMSD 1.87 Å
- 2Q7M chain A against the predicted model P20292: TM-score 0.91, RMSD 1.88 Å
- 2Q7M chain A against the predicted model P20292: TM-score 0.91, RMSD 1.88 Å
- 2Q7R chain E against the predicted model P20292: TM-score 0.91, RMSD 1.95 Å
- 2Q7R chain E against the predicted model P20292: TM-score 0.91, RMSD 1.95 Å
- 2Q7M chain D against the predicted model P20292: TM-score 0.91, RMSD 1.83 Å
- 2Q7M chain D against the predicted model P20292: TM-score 0.91, RMSD 1.83 Å
Elsewhere
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