UniProt P20273
B-cell receptor CD22 (P20273)
B-cell receptor CD22 (UniProt P20273): 4 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20273
- Protein
- B-cell receptor CD22
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 5
Structures
5 records of P20273 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VKJ | Crystal structure of human CD22 ig domains 1-3 | x-ray diffraction | A | NAG, BMA, MAN | — |
| 5VKM | Crystal structure of human CD22 Ig domains 1-3 in complex with alpha 2-6 sialyllactose | x-ray diffraction | A | NAG, BMA, MAN, GAL, SIA | — |
| 5VKM | Crystal structure of human CD22 ig domains 1-3 in complex with alpha 2-6 sialyllactose | x-ray diffraction | A | NAG, BMA, MAN, GAL, SIA | — |
| 5VL3 | CD22 D1-D3 in complex with therapeutic Fab epratuzumab | x-ray diffraction | Q, R, S, T | NAG, BMA, MAN | — |
| P20273 | AlphaFold monomer V2.0 prediction for B-cell receptor CD22 (P20273) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5VL3 chain S against the predicted model P20273: TM-score 0.97, RMSD 1.18 Å
- 5VL3 chain R against the predicted model P20273: TM-score 0.96, RMSD 1.46 Å
- 5VL3 chain Q against the predicted model P20273: TM-score 0.96, RMSD 1.60 Å
- 5VL3 chain T against the predicted model P20273: TM-score 0.96, RMSD 1.30 Å
- 5VKM chain A against the predicted model P20273: TM-score 0.93, RMSD 1.98 Å
- 5VKM chain A against the predicted model P20273: TM-score 0.93, RMSD 1.98 Å
- 5VKJ chain A against the predicted model P20273: TM-score 0.89, RMSD 2.47 Å
Elsewhere
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