UniProt P18934
NADH-ubiquinone oxidoreductase chain 4L (P18934)
NADH-ubiquinone oxidoreductase chain 4L (UniProt P18934), EC 7.1.1.2: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P18934
- Protein
- NADH-ubiquinone oxidoreductase chain 4L
- EC
- 7.1.1.2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 11 · 4 records with a druggable one
Structures
5 records of P18934 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B9Z | Drosophila melanogaster complex I in the Active state (Dm1) | electron microscopy | K | PC1 | 4 (best 0.87) |
| 8BA0 | Drosophila melanogaster complex I in the Twisted state (Dm2) | electron microscopy | K | — | 2 (best 0.81) |
| 8ESW | Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | electron microscopy | 4L | — | 2 (best 0.86) |
| 8ESZ | Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | electron microscopy | 4L | CDL | 3 (best 0.87) |
| P18934 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 4L (P18934) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8BA0 chain K against the predicted model P18934: TM-score 0.85, RMSD 2.03 Å
- 8ESZ chain 4L against the predicted model P18934: TM-score 0.83, RMSD 2.36 Å
- 8B9Z chain K against the predicted model P18934: TM-score 0.83, RMSD 2.38 Å
- 8ESW chain 4L against the predicted model P18934: TM-score 0.82, RMSD 2.29 Å
Elsewhere
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