UniProt P18564
Integrin beta-6 (P18564)
Integrin beta-6 (UniProt P18564): 16 experimental structures on GenesisL1, 11 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P18564
- Protein
- Integrin beta-6
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 46 · 5 records with a druggable one
Structures
16 records of P18564 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UM8 | Crystal structure of alpha V beta 6 | x-ray diffraction | B, D | — | — |
| 4UM8 | Crystal structure of alpha V beta 6 | x-ray diffraction | B, D | — | — |
| 4UM9 | Crystal structure of alpha V beta 6 with peptide | x-ray diffraction | B, D | — | — |
| 5FFG | Crystal structure of integrin alpha V beta 6 head | x-ray diffraction | B | — | — |
| 5FFO | Integrin alpha V beta 6 in complex with pro-TGF-beta | x-ray diffraction | B, F | NAG, BMA, MAN, MN | — |
| 5FFO | Integrin alpha V beta 6 in complex with pro-TGF-beta | x-ray diffraction | B, F | — | — |
| 5NEM | Localised reconstruction of alpha V beta 6 bound to foot and mouth disease virus O panasia - pose a. | electron microscopy | B | NAG | — |
| 5NER | Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A… | electron microscopy | B | NAG | 6 (best 0.81) |
| 5NER | Localised reconstruction of alpha V beta 6 bound to foot and mouth disease virus O panasia - pose a… | electron microscopy | B | NAG | — |
| 5NET | Localised reconstruction of integrin alpha V beta 6 bound to foot and mouth disease virus O1 manisa… | electron microscopy | B | NAG | — |
| 5NEU | Localised reconstruction of integrin alpha V beta 6 bound to foot and mouth disease virus O1 manisa… | electron microscopy | B | MG, CA | — |
| 9CZ7 | Crystal structure of integrin avb6 headpiece in complex with compound 12 | x-ray diffraction | B | MG, CA, A1A6A, NAG | 9 (best 0.78) |
| 9CZA | Crystal structure of integrin avb6 headpiece in complex with compound 18 | x-ray diffraction | B | NAG, MG, CA, A1A6B | 10 (best 0.79) |
| 9CZD | Crystal structure of integrin avb6 headpiece in complex with compound 30 | x-ray diffraction | B | NAG, A1A6H, MG, CA | 11 (best 0.80) |
| 9CZF | Crystal structure of integrin avb6 headpiece in complex with compound MORF-627 | x-ray diffraction | B | MG, CA, A1A6I, NAG, CL | 10 (best 0.78) |
| P18564 | AlphaFold monomer V2.0 prediction for integrin beta-6 (P18564) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 9 records
- CA · Calcium ion · in 5 records
- MG · Magnesium ion · in 5 records
- A1A6A · (2S)-phenyl{(3S)-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy]pyrrolidin-1-yl}acetic acid · in 1 record
- A1A6B · (2S)-(2-cyclopropylphenyl){(3R)-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy]pyrrolidin-1-yl}acetic acid · in 1 record
- A1A6H · (2S)-{5-fluoro-2-[(2S)-oxan-2-yl]phenyl}{(3R)-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy]pyrrolidin-1-yl}acetic acid · in 1 record
- A1A6I · (2S)-{5-fluoro-2-[(6S)-5-oxaspiro[2.5]octan-6-yl]phenyl}{(3R)-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy]pyrrolidin-1-yl}acetic acid · in 1 record
- BMA · beta-D-mannopyranose · in 1 record
- CL · Chloride ion · in 1 record
- MAN · alpha-D-mannopyranose · in 1 record
- MN · Manganese (II) ion · in 1 record
Elsewhere
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