UniProt P16649
General transcriptional corepressor TUP1 (P16649)
General transcriptional corepressor TUP1 (UniProt P16649): 6 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P16649
- Protein
- General transcriptional corepressor TUP1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
7 records of P16649 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ERJ | Crystal structure of the C-terminal WD40 domain of TUP1 | x-ray diffraction | A, B, C | — | — |
| 1ERJ | Crystal structure of the C-terminal WD40 domain of TUP1 | x-ray diffraction | A, B, C | — | — |
| 3VP8 | Crystal structure of the N-terminal domain of the yeast general corepressor Tup1p | x-ray diffraction | A, B, C, D | — | — |
| 3VP8 | Crystal structure of the N-terminal domain of the yeast general corepressor TUP1P | x-ray diffraction | A, B, C, D | — | — |
| 3VP9 | Crystal structure of the N-terminal domain of the yeast general corepressor Tup1p mutant | x-ray diffraction | A, B | — | — |
| 3VP9 | Crystal structure of the N-terminal domain of the yeast general corepressor TUP1P mutant | x-ray diffraction | A, B | — | — |
| P16649 | AlphaFold monomer V2.0 prediction for general transcriptional corepressor TUP1 (P16649) | predicted | A | — | 3 (best 0.81) |
Experiment against prediction
- 1ERJ chain B against the predicted model P16649: TM-score 1.00, RMSD 0.21 Å
- 1ERJ chain B against the predicted model P16649: TM-score 1.00, RMSD 0.21 Å
- 1ERJ chain C against the predicted model P16649: TM-score 1.00, RMSD 0.22 Å
- 1ERJ chain C against the predicted model P16649: TM-score 1.00, RMSD 0.22 Å
- 1ERJ chain A against the predicted model P16649: TM-score 1.00, RMSD 0.30 Å
- 1ERJ chain A against the predicted model P16649: TM-score 1.00, RMSD 0.30 Å
- 3VP8 chain C against the predicted model P16649: TM-score 0.93, RMSD 0.85 Å
- 3VP8 chain C against the predicted model P16649: TM-score 0.93, RMSD 0.85 Å
- 3VP8 chain A against the predicted model P16649: TM-score 0.90, RMSD 1.05 Å
- 3VP8 chain A against the predicted model P16649: TM-score 0.90, RMSD 1.05 Å
Elsewhere
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