UniProt P16622
Ferrochelatase, mitochondrial (P16622)
Ferrochelatase, mitochondrial (UniProt P16622), EC 4.99.1.1: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P16622
- Protein
- Ferrochelatase, mitochondrial
- EC
- 4.99.1.1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
7 records of P16622 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L8X | Crystal Structure of Ferrochelatase from the Yeast, Saccharomyces cerevisiae, with Cobalt(II) as… | x-ray diffraction | A, B | — | — |
| 1L8X | Crystal structure of ferrochelatase from the yeast, saccharomyces cerevisiae, with COBALT(II) as… | x-ray diffraction | A, B | — | — |
| 1LBQ | The crystal structure of Saccharomyces cerevisiae ferrochelatase | x-ray diffraction | A, B | — | — |
| 1LBQ | The crystal structure of saccharomyces cerevisiae ferrochelatase | x-ray diffraction | A, B | — | — |
| 7L78 | H235C variant of Yeast Ferrochelatase | x-ray diffraction | A, B | CHD | 9 (best 0.82) |
| 7L78 | H235C variant of yeast ferrochelatase | x-ray diffraction | A, B | CHD | — |
| P16622 | AlphaFold monomer V2.0 prediction for ferrochelatase, mitochondrial (P16622) | predicted | A | — | — |
Ligands
- CHD · Cholic acid · in 2 records
Experiment against prediction
- 7L78 chain A against the predicted model P16622: TM-score 1.00, RMSD 0.44 Å
- 7L78 chain A against the predicted model P16622: TM-score 1.00, RMSD 0.44 Å
- 1LBQ chain B against the predicted model P16622: TM-score 0.99, RMSD 0.60 Å
- 1LBQ chain B against the predicted model P16622: TM-score 0.99, RMSD 0.60 Å
- 1L8X chain B against the predicted model P16622: TM-score 0.99, RMSD 0.66 Å
- 1L8X chain B against the predicted model P16622: TM-score 0.99, RMSD 0.66 Å
- 7L78 chain B against the predicted model P16622: TM-score 0.99, RMSD 0.69 Å
- 7L78 chain B against the predicted model P16622: TM-score 0.99, RMSD 0.69 Å
- 1LBQ chain A against the predicted model P16622: TM-score 0.99, RMSD 0.80 Å
- 1LBQ chain A against the predicted model P16622: TM-score 0.99, RMSD 0.80 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.