UniProt P16603
NADPH--cytochrome P450 reductase (P16603)
NADPH--cytochrome P450 reductase (UniProt P16603): 8 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P16603
- Protein
- NADPH--cytochrome P450 reductase
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
9 records of P16603 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BF4 | A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of… | x-ray diffraction | A, B | — | — |
| 2BF4 | A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of… | x-ray diffraction | A, B | — | — |
| 2BN4 | A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of… | x-ray diffraction | A, B | — | — |
| 2BN4 | A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of… | x-ray diffraction | A, B | — | — |
| 2BPO | Crystal structure of the yeast CPR triple mutant: D74G, Y75F, K78A. | x-ray diffraction | A, B | — | — |
| 2BPO | Crystal structure of the yeast cpr triple mutant: D74G, Y75F, K78A. | x-ray diffraction | A, B | — | — |
| 3FJO | Structure of chimeric YH CPR | x-ray diffraction | A | — | — |
| 3FJO | Structure of chimeric yh cpr | x-ray diffraction | A | — | — |
| P16603 | AlphaFold monomer V2.0 prediction for NADPH--cytochrome P450 reductase (P16603) | predicted | A | — | 5 (best 0.80) |
Experiment against prediction
- 2BF4 chain A against the predicted model P16603: TM-score 1.00, RMSD 0.40 Å
- 2BF4 chain A against the predicted model P16603: TM-score 1.00, RMSD 0.40 Å
- 2BPO chain A against the predicted model P16603: TM-score 1.00, RMSD 0.45 Å
- 2BPO chain A against the predicted model P16603: TM-score 1.00, RMSD 0.45 Å
- 2BN4 chain B against the predicted model P16603: TM-score 0.99, RMSD 0.67 Å
- 2BN4 chain B against the predicted model P16603: TM-score 0.99, RMSD 0.67 Å
- 2BN4 chain A against the predicted model P16603: TM-score 0.99, RMSD 0.90 Å
- 2BN4 chain A against the predicted model P16603: TM-score 0.99, RMSD 0.90 Å
- 3FJO chain A against the predicted model P16435: TM-score 0.71, RMSD 1.39 Å
- 3FJO chain A against the predicted model P16435: TM-score 0.71, RMSD 1.39 Å
Elsewhere
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