UniProt P16452
Protein 4.2 (P16452)
Protein 4.2 (UniProt P16452): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P16452
- Protein
- Protein 4.2
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 51 · 8 records with a druggable one
Structures
19 records of P16452 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7TVZ | Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation | electron microscopy | E | — | 9 (best 0.86) |
| 7TVZ | Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation | electron microscopy | E | — | — |
| 7TW0 | Cryo-EM structure of human band 3-protein 4.2 complex in vertical conformation | electron microscopy | E | — | — |
| 7TW1 | Cryo-EM structure of human band 3-protein 4.2 complex (B2P2VERTICAL) | electron microscopy | E, F | — | — |
| 7TW3 | Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell | electron microscopy | E | — | — |
| 7TW5 | Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell | electron microscopy | E | — | — |
| 7TW6 | Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell | electron microscopy | E | — | — |
| 7UZS | Protein 4.2 (local refinement from consensus reconstruction of ankyrin complex classes) | electron microscopy | X | — | 7 (best 0.79) |
| 7UZS | Protein 4.2 (local refinement from consensus reconstruction of ankyrin complex classes) | electron microscopy | X | — | — |
| 7V0K | Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map) | electron microscopy | X | CLR, PIO | 6 (best 0.85) |
| 7V0Q | Local refinement of protein 4.2, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | X | — | 7 (best 0.78) |
| 7V0Q | Local refinement of protein 4.2, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | X | — | — |
| 8CS9 | Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex | electron microscopy | X | PIO | 5 (best 0.83) |
| 8CSL | Sub-tomogram averaging of erythrocyte ankyrin-1 complex | electron microscopy | X | — | 5 (best 0.75) |
| 8CSW | Local refinement of protein 4.2 in Class 2 of erythrocyte ankyrin-1 complex | electron microscopy | X | — | 7 (best 0.78) |
| 8CSW | Local refinement of protein 4.2 in class 2 of erythrocyte ankyrin-1 complex | electron microscopy | X | — | — |
| 8CTE | Class 2 of erythrocyte ankyrin-1 complex (Composite map) | electron microscopy | X | — | 5 (best 0.84) |
| 8CTE | Class 2 of erythrocyte ankyrin-1 complex (composite MAP) | electron microscopy | X | — | — |
| P16452 | AlphaFold monomer V2.0 prediction for protein 4.2 (P16452) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8CSL chain X against the predicted model P16452: TM-score 0.98, RMSD 1.36 Å
- 8CS9 chain X against the predicted model P16452: TM-score 0.98, RMSD 1.36 Å
- 7V0Q chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 7V0Q chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 7UZS chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 7UZS chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 8CSW chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 8CSW chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 7V0K chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
- 8CTE chain X against the predicted model P16452: TM-score 0.98, RMSD 1.37 Å
Elsewhere
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