UniProt P16317
secreted protease C (P16317)
secreted protease C (UniProt P16317), EC 3.4.24.-: 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P16317
- Protein
- secreted protease C
- EC
- 3.4.24.-
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 6 records with a druggable one
Structures
19 records of P16317 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GO7 | The metzincin's methionine: PrtC M226C-E189K double mutant | x-ray diffraction | P | CA, ZN, PO4 | 4 (best 0.55) |
| 1GO7 | The METZINCIN'S methionine: prtc M226C-E189K double mutant | x-ray diffraction | P | — | — |
| 1GO8 | The metzincin's methionine: PrtC M226L mutant | x-ray diffraction | P | CA, ZN, PO4 | 4 (best 0.55) |
| 1GO8 | The METZINCIN'S methionine: prtc M226L mutant | x-ray diffraction | P | — | — |
| 1K7G | PrtC from Erwinia chrysanthemi | x-ray diffraction | A | CA, ZN, PO4 | 5 (best 0.55) |
| 1K7G | Prtc from erwinia chrysanthemi | x-ray diffraction | A | — | — |
| 1K7I | PrtC from Erwinia chrysanthemi: Y228F mutant | x-ray diffraction | A | CA, ZN | 4 (best 0.55) |
| 1K7I | Prtc from erwinia chrysanthemi: Y228F mutant | x-ray diffraction | A | — | — |
| 1K7Q | PrtC from Erwinia chrysanthemi: E189A mutant | x-ray diffraction | A | CA, ZN | 4 (best 0.52) |
| 1K7Q | Prtc from erwinia chrysanthemi: E189A mutant | x-ray diffraction | A | — | — |
| 3HB2 | PrtC methionine mutants: M226I | x-ray diffraction | P | — | — |
| 3HB2 | Prtc methionine mutants: M226I | x-ray diffraction | P | — | — |
| 3HBU | PrtC methionine mutants: M226H DESY | x-ray diffraction | P | — | — |
| 3HBU | Prtc methionine mutants: M226H desy | x-ray diffraction | P | — | — |
| 3HBV | PrtC methionine mutants: M226A in-house | x-ray diffraction | P | — | — |
| 3HBV | Prtc methionine mutants: M226A in-house | x-ray diffraction | P | — | — |
| 3HDA | PrtC methionine mutants: M226A_DESY | x-ray diffraction | P | — | — |
| 3HDA | Prtc methionine mutants: M226A_DESY | x-ray diffraction | P | — | — |
| P16317 | AlphaFold monomer V2.0 prediction for serralysin C (P16317) | predicted | A | — | 5 (best 0.69) |
Ligands
Experiment against prediction
- 3HB2 chain P against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 3HB2 chain P against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 1K7Q chain A against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 1K7Q chain A against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 3HBU chain P against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 3HBU chain P against the predicted model P16317: TM-score 1.00, RMSD 0.24 Å
- 1GO8 chain P against the predicted model P16317: TM-score 1.00, RMSD 0.28 Å
- 1GO8 chain P against the predicted model P16317: TM-score 1.00, RMSD 0.28 Å
- 1K7G chain A against the predicted model P16317: TM-score 1.00, RMSD 0.28 Å
- 1K7G chain A against the predicted model P16317: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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